International Medical Journal

Journal ID : IMJ-12-03-2022-1325

Total View : 564

Title : Childhood and adolescent cancers in Morocco Epidemiological profile and risk factors

Abstract : Cancer in children and adolescents represents only a small fraction of the global cancer burden. However, the different characteristics of adult cancers require the construction of large-scale studies, conducted mainly on a national and even international scale, in order to collect statistically significant data. Our research is part of this effort to provide a reference of knowledge on this type of cancer in Morocco. This is a descriptive retrospective epidemiological study at the two public oncology centers from the records of patients under 20 years of age with cancer diagnosed between January 2014 and December 2018 at the oncology center in Marrakech and between January 2014 and 30/06/2019 at the oncology center in Agadir. Data collection concerned gender, age, origin (city), setting (urban/rural and cancer location. The data were entered and analyzed on SPSS version 24. The incidence of cancer in children and adolescents under 20 years of age was estimated at (7.26/100 000) in the Marrakech Safi region and (8.87/100 000) in the Souss Massa region. They represented respectively 2% and 3% of all registered cases. Among children aged between 0 and 14 years, the incidence of cancer in the global population is estimated at (4.17/100,000) in the Marrakech Safi region and (5.49/100,000) in the Souss Massa region. They represented respectively 1% and 1.6% of all registered cases. The patients are mainly of both sexes without dominance of one over the other, coming from urban areas and from rural areas. Among the most frequent types of cancers among cancer patients under 20 years of age are leukemia, brain and nervous system, bone, Hodgkin's lymphoma. This study has increased knowledge of childhood and adolescent cancers in Morocco and accelerated research towards a better understanding of the most likely risk factors and to strengthen prevention efforts..
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International Medical Journal

Journal ID : IMJ-10-03-2022-1322

Total View : 366

Title : A Prospective study of Conservative versus Operative management of intra-abdominal solid organ injury in Tertiary care center.

Abstract : Trauma is a major worldwide problem. It is one of the major causes of death in industrial and civilized countries. Trauma is the most common cause of death between the age of 15 & 44 years and 3rd most common cause of death worldwide regardless of age. The most significant change in trauma patient's care over the last decades is represented by the switch to selective non-operative management (NOM)7. This was a study done among the patients admitted with alleged history of blunt abdominal trauma in tertiary care hospital. Total 50 patients were taken in the present study. The study participants are evaluated and recorded various variables like mechanism of injury, hemodynamic stability, and organ injured, grading of injury etc. All patients with hemodynamic stability were managed in surgical ICU with close observation, serial investigations & immobilization. Only 3(6%) patients required operative management later on in NOM group. Total 15(30%) patients were managed operatively. All patients were kept in surgical ICU. In OP group incidence of spleenic injuries is highest (47%). Hemodynamic instability remains the most important parameter in decision making between conservative and operative management of trauma patients with solid organ injury. Most of the patients were managed conservatively in intensive care unit with regular monitoring and serial CT scan. Non operative line of management is now considered the line of treatment for patients with intra-abdominal organ injury that are hemodynamically stable..
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International Medical Journal

Journal ID : IMJ-08-03-2022-1316

Total View : 473

Title : The Impact of Parental Education Styles on Smoking as Dangerous Behavior in Adolescents

Abstract : In the program for prevention and protection against addictions, the family has an irreplaceable role. The aim of this research is to determine the role of parenting education styles in motivating and creating learning strategies for the prevention of risky behaviors of children. A quantitative analytical study was conducted on a sample of 600 respondents, students from primary and secondary schools on the territory of the Polog region in North Macedonia. The scale designed to assess parenting education styles - the "Egna Minnen Batraffande Uppfostran" (EMBU), was applied, as well as the survey questionnaire from the "Global Survey on Adolescent Health". The result shown that by increasing the value of the subclass "emotional warmness" of the mother, the risk of developing risky behavior among children in terms of cigarette smoking is reduced for 2.3% ; by increasing the value of subclass "favoring" of the mother per unit score, the risk of developing risky behavior among children in terms of cigarette smoking is increased for 12.6%, by increasing the value of the subclass "inconsistency" of the father per unit score, the risk of developing risky behavior among children in terms of smoking cigarettes is increased for 7.8%, by increasing the value of the subclass "rejection" of the father per unit score, the risk of developing risky behavior among children in terms of smoking cigarettes is increased for 3.5% and by increasing the value of the subclass "favoring" of the father per unit score, the risk of developing risky behavior among children in terms of smoking cigarettes is increased for 8.7%. The results of research have shown that the educational styles of parents have a significant impact on the risky behavior of adolescents in terms of cigarette smoking..
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International Medical Journal

Journal ID : IMJ-06-03-2022-1312

Total View : 446

Title : ASSOCIATION OF SKIN TAGS WITH METABOLIC SYNDROME

Abstract : Skin tags or Acrochordons present as pedunculated papules or tumors that are most commonly seen over the eyelids, neck, axillae, and groin. They are usually asymptomatic and are treated for cosmetic lesions. Metabolic syndrome (Met S) comprise of a cluster of risk factors of metabolic origin, which are accompanied by increased risk of cardiovascular disease and type-2 diabetes mellitus. To identify, the patients with skin tags and their positive relationship with Metabolic Syndrome, among the patients attending the Dermatology & Venereology department in a tertiary care teaching hospital. A pre-structured and pre-tested Proforma was used to collect data from 100 patients attending Dermatology outpatient department in a tertiary care teaching hospital. A total of 62% of the participants with skin tags had underlying metabolic syndrome. The proportion of people with metabolic syndrome gradually increased with increasing age. The association between age and metabolic syndrome was statistically significant (P value 0.002). Although there was no statistically significant association between gender and metabolic syndrome in study population. The proportion of people with Acanthosis. Nigricans gradually increased with increasing age. There was a statistically significant association between the skin tags and metabolic syndrome (P value < 0.016). We propose to consider skin tags as cutaneous findings frequently associated with the risk factors for Metabolic Syndrome and heart disease, and recommended that these patients should be carefully evaluated for Metabolic Syndrome and heart disease. Skin tag is an indicator of peripheral insulin resistance which may be an early marker of metabolic syndrome..
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International Medical Journal

Journal ID : IMJ-05-03-2022-1311

Total View : 478

Title : Relation between Heat Shock Protein 70 (HSP-70) Levels and Disease Severity in Chronic Urticaria

Abstract :

Chronic urticaria (CU) is a common dermatological condition that may occur spontaneously or may be induced by specific triggers. Heat shock proteins (HSPs) are molecular chaperones with critical roles in protein synthesis. They are induced in response to physiological and environmental stressors. The present study aimed to investigate the relation between serum levels of HSP-70 and severity of chronic urticaria. The present case control study included 70 patients with chronic spontaneous urticaria (CSU). In addition, there were 25 age and sex-matched healthy control. The severity of their urticaria symptoms were assessed using Urticaria Activity Score (UAS). Symptoms were classified as mild, moderate or intense. Serum levels of HSP70 measured by ELISA method. Patients had significantly higher HSP-70 levels when compared with controls [median (IQR): 62.0 (0.23-0.91 versus 0.26 (0.2-0.45) ng/ml, p0.001] (Fig. 1). Patients group included 29 patients (41.4 %) with mild disease, 29 patients (41.4 %) with moderate disease and 12 patients (17.2 %). Comparison between patients with different disease severity grades shows signification relation between disease severity grade and HSP-70 levels. Logistic regression multivariate analysis identified elevated HSP-70 levels as significant predictor of significant (moderate/intense) CU. The present study found a significant relation between increased serum HSP-70 levels and increased disease severity in CU patients.

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International Medical Journal

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Submission Deadline ( Vol 30 , Issue 06 )
20 Jun 2023

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Publish On ( Vol 30 , Issue 05 )
31 May 2023