International Medical Journal (ISSN:13412051)

Aim and Scope

Aim-

International Medical Journal ISSN: (13412051) is an international open-access journal publishes twelve times each year. The "International Medical Journal" is a peer-reviewed, monthly, online international research journal, which publishes original articles, research articles, review articles with top-level work from all areas of Medical Science Research and their application including Aetiology, bioengineering, biomedicine, cardiology, chiropody, ENT etc. Researchers in all Medical Science and Pharmacy fields are encouraged to contribute articles based on recent research. Journal publishes research articles and reviews within the whole field of Medical Science and Pharmacy Research, and it will continue to provide information on the latest trends and developments in this ever-expanding subject. International Medical Journal journal covers almost all disciplines of Medical Science and Pharmacy. Researchers and students of M.B.B.S, M.D., D.T.C.D., GYNE., M.S., M.Pharma, And PhD are requested to send their original research articles to International Medical Journal.

Scope-

International Medical Journal ISSN: (13412051) is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:

Anatomy Physiology Biochemistry Pharmacology
Pathology Forensic medicine Microbiology Community Medicine
Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology
Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases
Anaesthesia Cancer research Neurosurgery Orthopedics

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Latest Journals
International Medical Journal
Journal ID : IMJ-06-02-2020-214
Total View : 379

Abstract : Diabetes mellitus is a group of metabolic disorders characterized by lack of blood glucose homeostasis. This results from defects in insulin secretion, insulin action, or both. Optimal glycemic control is fundamental in the management of DM. It is considered the main therapeutic objective for preventing the development and progression of diabetic micro and macro vascular complications. The aim of this study is to assess the glycemic control of diabetic patients by the correlation between FPG and PPG with HbA1c. More than 40 original research articles using online database were critically reviewed. It was found that the correlation between PPG and HbA1c is stronger than that between FPG and HbA1c. However, some studies revealed a stronger correlation between FBG and HbA1c than that between PPG and HbA1c. The correlation coefficient (r) ranged from 0.44-0.81 for PPG and from 0.28-0.81 (Table 1). Patients who achieved 2-h PPG within the reference limit better attained target HbA1c values than patients who achieved FPG within reference limit. In other words, decreasing PPG accounted for a greater decrease in HbA1c than decrease in FPG. Therefore, control of PPG is more reliable for achieving target HbA1c ˂7% than FPG. Both FPG and PPG levels were correlated with HbA1c, but higher correlation was observed between HbA1c and PPG than FPG. HbA1c is the best standard in assessing glycemic control with the availability of standardized methods.
Full article
International Medical Journal
Journal ID : IMJ-06-02-2020-213
Total View : 354

Abstract : Systemic lupus erythematosus (SLE) is a chronic multi-system inflammatory connective tissue disorder, affecting kidneys in about 50% of patients. The laboratory tools used to determine kidney affection are modest and relatively inaccurate in their ability to detect SLE activity and lupus nephritis flare. Therefore, new biomarkers for proper detection of SLE activity and lupus renal disease have to be searched. To investigate serum adiponectin as a marker of SLE activity and lupus nephritis. 90 participants were involved and classified into 4 main groups; group I included 36 healthy volunteers as control group, group II included 18 patients with active SLE with lupus nephritis, group III included 18 patients with active SLE without lupus nephritis and group IV included 18 patients with inactive SLE. All participants were submitted to; urine analysis, complete blood count, fasting blood glucose, serum creatinine, liver function tests, serum complement 3 and 4, antinuclear antibody, anti-double stranded DNA level and serum adiponectin levels assays. Serum adiponectin levels were significantly higher in lupus nephritis group than in the other two SLE groups and controls. Adiponectin at a level >2.9μg/mL had a greater sensitivity 92.5% and specificity 98.3% for identifying SLE activity than both C 3 at a level < 44.4mg/dl with sensitivity 73.4% and specificity 75.6% and C4 at a level < 10.4mg/dl with sensitivity 65.2% and specificity 68.4%. Serum adiponectin could be used as an early marker for identifying SLE activity and lupus nephritis.
Full article
International Medical Journal
Journal ID : IMJ-06-02-2020-212
Total View : 141

Abstract : As social beings, in every activity communication activities are important things that must be done. As social beings, communication is an essential issue to do in each of their activities. One of the most important communications in human life is health communication. One of the most significant communications in human life is health communication. The purpose of health communication is as a means of delivering information or messages about health to the public. The purpose of health communication is as a way of delivering information or messages regarding health to the community. This study uses qualitative case study methods using primary and secondary data. This study employed a qualitative case study method with primary and secondary data. Primary data obtained through in-depth interviews (in-depth Primary data were obtained through in-depth interviews, interviews). Whereas secondary data is sourced from document review. while secondary data were taken from document reviews. The results of the study showed that health communication carried out by the Government of the Special Region of Yogyakarta in supporting the advocacy of No-Smoking Areas (KTR) policies through advocacy namely through the socialization of KTR policies, social support through collaboration with all elements of society and community empowerment through health education on the dangers of smoking to health to all elements of society in the Special Region of Yogyakarta. The results of the research revealed that the Special Region of Yogyakarta (DIY) carried out health communication in an effort to support advocacy for the Non-Smoking Area (KTR) through three ways: advocacy run by socializing KTR policies, social support performed through cooperation with all elements of society, and community empowerment implemented through health education regarding the dangers of smoking to health for all aspects of society in the area.
Full article
International Medical Journal
Journal ID : IMJ-06-02-2020-211
Total View : 140

Abstract : Placenta is the main factor in the pathogenesis theory for the mechanism of preeclampsia. Development of laboratory modality related preeclampsia is needed in therapy and prevention improvement. The aim of this study is to investigate optimization of the isolation protocol of primary cells of trophoblast and development of an in vitro model of preeclampsia by measuring the level of sFLT-1 and PIGF. This is an in vitro laboratory experimental study. Placenta tissue was obtained from term pregnancy with caesarean delivery. Trophoblast cells was isolated from the placenta in several steps and identified by Cytokeratin 7 (CK-7) expression using immunocytochemical method. Subsequently, cells were inducted with serum preeclampsia. Both sFLT-1 and PIGF level were measured with ELISA. Expressed CK-7 in the cytoplasm confirmed the cells were trophoblast cells. After induction, sFLT-1 increased and PIGF decreased compared with control. Trophoblast cells express CK-7 protein in their cytoplasm. Isolated trophoblast cells stained brown in the cytoplasm confirmed that these cells expressing CK-7 protein. Increased expression of sFlt-1 level in cells induced with preeclampsia serum corresponds with other research that overexpression of sFlt-1 causes clinical manifestation that is similar with hypertension in mice. Meanwhile, sFlt-1 is capable to break PIGF causing a decrease of it. Our result shown in line that PIGF level in cells induced with preeclampsia serum decreased compared with control. This protocol shown to be applicable in isolation of trophoblast cells in placenta and can be used as a basis to develop in vitro model of preeclampsia.
Full article
International Medical Journal
Journal ID : IMJ-06-02-2020-210
Total View : 195

Abstract : A 65-year-old Chinese lady presented to us with a 2-month history of progressive swelling in her right ear. It was a painless swelling associated with itchiness with occasional mucoid discharge. The initial diagnosis was right aural polyp which later biopsy was taken and histopathological examination revealed moderately differentiated squamous cell carcinoma of the right external ear canal. HRCT temporal bone was reported as lobulated soft tissue mass at the right external ear canal with preauricular nodes and pressure erosion of the bony EAC. The patient underwent radical surgery followed by a referral to the oncology team for further management.
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