International Medical Journal (ISSN:13412051)

Aim and Scope

Aim-

International Medical Journal ISSN: (13412051) is an international open-access journal publishes twelve times each year. The "International Medical Journal" is a peer-reviewed, monthly, online international research journal, which publishes original articles, research articles, review articles with top-level work from all areas of Medical Science Research and their application including Aetiology, bioengineering, biomedicine, cardiology, chiropody, ENT etc. Researchers in all Medical Science and Pharmacy fields are encouraged to contribute articles based on recent research. Journal publishes research articles and reviews within the whole field of Medical Science and Pharmacy Research, and it will continue to provide information on the latest trends and developments in this ever-expanding subject. International Medical Journal journal covers almost all disciplines of Medical Science and Pharmacy. Researchers and students of M.B.B.S, M.D., D.T.C.D., GYNE., M.S., M.Pharma, And PhD are requested to send their original research articles to International Medical Journal. Azerbaijan Medical Journal Gongcheng Kexue Yu Jishu/Advanced Engineering Science Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery

Scope-

International Medical Journal ISSN: (13412051) is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:

Anatomy Physiology Biochemistry Pharmacology
Pathology Forensic medicine Microbiology Community Medicine
Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology
Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases
Anaesthesia Cancer research Neurosurgery Orthopedics

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Latest Journals
International Medical Journal
Journal ID : IMJ-07-08-2021-832
Total View : 787

Abstract :

Low back pain is the fourth most common cause of disability-associated years worldwide. The sacral hiatus is an arched gap on the dorsal surface of the sacrum. It is a continuation of the sacral canal that contains the sacrococcygeal nerves, fibro-fatty tissue, and filum terminale. Anatomical variations of the sacral hiatus are associated with a high risk of low back pain. This study aimed to compare sacral hiatal parameters between patients with low back pain and healthy individual and determine the relationship between hiatal parameters and low back pain. A case-control study was conducted at PNS Shifa Hospital, Karachi, Pakistan, and Advanced Radiology Clinic, Karachi, Pakistan. After ethics review committee approval, 89 participants each were enrolled as cases and controls. Anteroposterior and lateral view X-rays of the lumbosacral spine were obtained. Hiatal apex and base were observed with reference to the level of the sacral vertebra. The length, width, and depth were measured using bony landmarks. There were 75 males and 103 females. The significant parameters were the hiatal shapes (p-value=0.047), apex (p-value=0.004), length (p-value<0.001) and width (p-value=0.008). The risk of low back pain was detected with shapes inverted U (O.R:1.621) and M (O.R:2.000), the apex at S1 (O.R:2.5) and S2 (O.R:1.713), base at S3 (O.R:1.33) and S4 (O.R: 1.2), variations in length, width, and depth. We identified hiatal shape, the apex and base (above S3), length (>30mm), and width (>13mm) as the risk factors for low back pain in this cohort.

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Full article
International Medical Journal
Journal ID : IMJ-07-08-2021-831
Total View : 619

Abstract : Migraine headache is an episodic primary headache disorder [1], [2], affecting about one in 10 adults worldwide [3]. Variety of drugs are available for both preventive [4], [5] and acute treatment [1], [4- 6]. However, many drugs may have varieties of adverse reaction [4- 8]. Recently, repetitive transcranial magnetic stimulation (rTMS) [9] has emerged as treatment option for episodic migraine [10], [11]. Single centre open labelled study. A total of 30 subjects with episodic migraine are included. Set of questionnaire used for recording on the headache frequency, headache severity during each attack, number of medications intake during migraine headache as well as for prophylaxis. All subjects will receive a total of 3 rTMS sessions, to be completed within a week. Upon completion, subjects will be evaluated with the same set of questionnaire. A month after completion of all rTMS sessions, 53.3% of subjects showed improvement of > 50% headache frequency. The number of rescue medications intake before rTMS was at mean 12.2 (SD 7.04) vs 2.57 (SD 2.14) at 4 weeks. Headache severity showed a mean score 7.4 (SD 1.55) reduced to 1.97 (SD 2.04) at the 1st week and 2.47 (SD: 1.81) on the 2nd week post rTMS. On the 3rd and 4th week, the mean score increased to 3.43 (SD 2.25) and 4.13 (SD 1.72) respectively. Treatment with rTMS is beneficial among Malaysia population suffer from episodic migraine. Improvement in terms of headache frequency, headache severity as well as reduction of numbers of abortive medications intake have been reported and confirmed in this study..
Full article
International Medical Journal
Journal ID : IMJ-07-08-2021-830
Total View : 691

Abstract :

Coronavirus Disease 2019 (COVID-19) was first reported in December 2019, in the City of Wuhan, China. Within the span of a few weeks, the disease had spread to other regions of China and eventually to different parts of the world. COVID 19 has affected 221 countries and territories around the world, with a total of 111,970,286 positive cases and 2,478,354 deaths as on 22nd February 2021. Accurate disease diagnosis (for the SARS-Cov-2 virus and variants), coupled to patient isolation are currently critical strategies in restricting disease spread. Due to lack of time during this pandemic the diagnostics assays were not adequately validated. Infected individuals at times could potentially be missed by real-time reverse transcription polymerase chain reaction (rRT-PCR) for SARS-CoV-2 tests due to incorrect/inefficient sampling procedure, low limit of detection and epidemiology of the virus. rRT-PCR test results should be interpreted in conjunction with clinical examination and Computed Tomography (CT), particularly in suspected symptomatic individuals or those with epidemiological history of contact with known COVID-19 cases. Considering the above-mentioned constraints, the current scenario demands rapid and point-of-care tests for detection of SARS-CoV-2 in remote locations. To date, there is no reliable commercially available antigen detection kit. The infected subjects reveal low levels of antibodies against SARS-CoV-2 through the early period of infection. In addition, techniques such as, Digital RT-PCR technology and isothermal RNA amplification with electrochemical biosensors are some of the new technologies currently being developed to provide sensitive and specific SARS-Cov-2 antigen detection. The newly reported variant, SARS-CoV-2 VUI 202012/01 may not influence diagnostic outcomes as worldwide most PCR assays use two or more (including RdRp/ E/ N) reliable gene targets, besides S gene.

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Full article
International Medical Journal
Journal ID : IMJ-06-08-2021-829
Total View : 0

Abstract : Current literature indicates a correlation between type 2 diabetes mellitus (T2DM), Helicobacter (H) pylori infection, and chronic inflammation. Antidiabetic therapies were involved in metabolic strategies for mitigating chronic inflammation. The current study aims to assess the impact of antidiabetic therapies on lipids and adipocytokines production in T2DM patients with H. pylori infection. The study was conducted on 127 participants allocated to 102 T2DM patients and 25 healthy subjects. The diabetic patients were subdivided into six groups according to metformin administration (mono, and dual therapy). Diabetic untreated patients showed significant (P< 0.001) elevations in the levels of body mass index, microalbuminuria, blood glucose, glycosylated hemoglobin (HbA1c), H. pylori immunoglobulin-G, and lipid profile parameters compared to healthy controls. Moreover, C-reactive protein (CRP) and leptin concentrations exhibited a significant (P< 0.001) increase, while adiponectin levels observed a marked (P< 0.001) decrease in diabetic patients compared to healthy controls. Treatment with antidiabetic therapy showed a significant (P< 0.05) amelioration in the levels of blood glucose, HbA1c%, cholesterol, low-density lipoproteins (LDL), cardio-risk factors, CRP, leptin, and adiponectin compared to diabetic-untreated patients. Notably, H. pylori infection revealed noticeable positive correlations with HbA1c%, CRP, triglycerides, and leptin/adiponectin ratio in all treated-diabetic groups. The study reveals the synergistic impact of T2DM with H. pylori infection in the increased inflammatory condition and diabetic complication. The marked amelioration in the glycemic state after treatment with antidiabetic therapies was associated with improvement in lipids, CRP, and adipocytokine levels among diabetic-treated patients with H. pylori infection..
Full article
International Medical Journal
Journal ID : IMJ-05-08-2021-827
Total View : 350

Abstract : As of June 26, 2021, there were 181 million patients with coronavirus 2019 (COVID-19) worldwide, of whom more than 3.9 million had died (https://coronavirus-monitor.info). Currently, there is an increase in the incidence of coronavirus infection in Kazakhstan in almost all regions due to a new highly contagious variant of COVID-19, Delta. According to statistics as of June 26, 2021, 414,712 Kazakhstani people fell ill, of whom 4,281 died (https://coronavirus-monitor.info/country/kazakhstan/)..
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