International Medical Journal (ISSN:13412051)

Aim and Scope

Aim-

International Medical Journal ISSN: (13412051) is an international open-access journal publishes twelve times each year. The "International Medical Journal" is a peer-reviewed, monthly, online international research journal, which publishes original articles, research articles, review articles with top-level work from all areas of Medical Science Research and their application including Aetiology, bioengineering, biomedicine, cardiology, chiropody, ENT etc. Researchers in all Medical Science and Pharmacy fields are encouraged to contribute articles based on recent research. Journal publishes research articles and reviews within the whole field of Medical Science and Pharmacy Research, and it will continue to provide information on the latest trends and developments in this ever-expanding subject. International Medical Journal journal covers almost all disciplines of Medical Science and Pharmacy. Researchers and students of M.B.B.S, M.D., D.T.C.D., GYNE., M.S., M.Pharma, And PhD are requested to send their original research articles to International Medical Journal.

Scope-

International Medical Journal ISSN: (13412051) is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:

Anatomy Physiology Biochemistry Pharmacology
Pathology Forensic medicine Microbiology Community Medicine
Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology
Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases
Anaesthesia Cancer research Neurosurgery Orthopedics

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Latest Journals
International Medical Journal
Journal ID : IMJ-27-02-2020-296
Total View : 106

Abstract : Although intensively studied, Parkinson's disease (PD) continues to challenge neurologists, particularly in its advanced stages. While initial oral treatment with levodopa improves motor symptoms, conventional treatment loses its effectiveness as the disease progresses, other therapies, such as continuous levodopa/carbidopa intestinal gel (LCIG) administration, being required. In recent years, perspectives have shifted, neurologists considering PD a complex impairment of several systems causing motor and non-motor symptoms. This study’s aim was to evaluate non-motor symptoms in Romanian patients with advanced PD undergoing continuous LCIG administration. In this cross-sectional observational study, two groups of 20 patients each were compared. The first group comprised PD diagnosed patients at Hoehn-Yahr (HY) stages II to IV receiving intermittent oral levodopa treatment; the second group comprised patients treated with the Duodopa® pump. All participants had been diagnosed with PD according to the United Kingdom Parkinson's Disease Society Brain Bank (UKPDSBB) Clinical Diagnostic Criteria. Motor and non-motor symptoms were recorded along with various data concerning the patient's age, duration of illness, gender, and comorbidities. The data were processed in SPSS v.20. Constipation, sleeping disorders, and mental disorders were observed more frequently in subjects receiving continuous LCIG administration (statistically significant). Although orthostatic hypotension, restless legs syndrome, and hypersalivation were less evident in patients receiving Duodopa® pump therapy, no statistical significance was observed. Anosmia and urinary incontinence remained unresolved despite antiparkinsonian therapy. Non-motor symptoms are essential components of the clinical picture in PD regardless of the therapeutic approach, with constipation, sleeping disorders, and mental disorders more prevalent in LCIG-treated patients.
Full article
International Medical Journal
Journal ID : IMJ-27-02-2020-295
Total View : 108

Abstract : Developments in the developing world over the last two decades have dramatically increased diabetes worldwide. Diabetes mellitus (DM) is an important public health problem. The presence of obesity, sedentary lifestyle and physical problems among the patients may increase the effect of diabetes. The objective of the current study was to determine the comparison of rural and urban areas among diabetic patients related to their physical activity. It was comparative cross sectional study. It was performed at Sialkot Medical Complex, Civil Hospital Sialkot, CMH Sialkot; Kashmir Hospital Sialkot Sameena Nisaar Hospital Sialkot. Convenient sampling (Non-Probability) was used for data collection. The calculated sample size was 400. Out of total 156 participants from rural areas, 2(1.3%) were sedentary, 13(8.3%) were under active, 12(7.7%) were under active regular light activity, 26(16.7%) were under active irregular, and 103(66%) were active. Out of 244 participants from urban areas 9(3.7%) were sedentary, 8(3.3%) were under active, 15(6.1%) were under active regular light activity, 58(23.8%) were under active irregular, and 154(63.1%) were active. P value calculated through chi square test show that there is difference in the level of aerobic activity level and people from rural areas had increased aerobic activity. Out of total 156 participants from rural areas, 140(89.7%) were not performing strength and flexibility. Out of total 244 participants from urban areas, 214(87.7%) were not performing strength and flexibility. Although, participants from rural are physical more active than participants from urban area in terms of aerobic activity but there is no difference in the strength and flexibility among both groups and as a whole participant from both group had equal level of physical activity.
Full article
International Medical Journal
Journal ID : IMJ-27-02-2020-294
Total View : 98

Abstract : This study focussed on evaluation of the addition of titanium dioxide (TiO2) nanoparticlesto conventional glass-ionomer (GC Universal Restorative Cement 2) on Vickers microhardness and shearbond strength. This study was an in-vitro experimental study. This study was carried out at Pakistan Instituteof Engineering and Applied Sciences (PIEAS). It was completed in two and half months i.e from 1stJanuary,2019 till 15 March,2019. Titania nano particles were added in conventional glass-ionomer (GCUniversal Restorative Cement 2) at 3%, 5% (w/w). Unblended powder was used as control group (Group 1)while glass-ionomer containing titania nano particles at 3% (w/w) was considered as (Group 2) and glass–ionomer containing titania nano particles at 5% (w/w) was considered as (Group 3). Diamond indentor wasused to measure surface microhardness. Cylinders of all groups (9.5X1mm) were prepared. Total of 9sample cylinders were prepared. Shear bond strength was measured using universal testing machine. Humananterior teeth were used to measure shear bond strength. Blocks of all three groups (4X4X1mm) wereattached to treated enamel and dentin surfaces. Total of 18 human anterior teeth were used to measure shearbond strength, 6 teeth for each group (3 for enamel and 3 for dentin). SEM analysis of specimen of flexuralstrength test was done before and after test. One-way ANOVA analysis was conducted to compare the shearbond strength and microhardness between the three groups. Post-hoc Tukey analysis was used to compareinter-group mean differences. An arbitrary significance value of 0.05 was considered to be significant. Alldata was entered and analysed using SPSS v 23.0. Results showed significant increase in microhardness(p<0.05) and significant increase in shear bond strength (p<0.05). Conclusions: GI-containing 3% and 5%(w/w) TiO2 nanoparticles are restorative material with enhanced mechanical properties. This interestingexperimental Glass-ionomer may be used for higher stress-bearing area restorations such as Class I and II.
Full article
International Medical Journal
Journal ID : IMJ-27-02-2020-293
Total View : 113

Abstract : Nodal metastasis is fairly common in Oral Squamous Cell Carcinoma and is hard to detect on physical examination. Thus, a cheap and reliable method for detection of lymph node metastasis is required. The objective of current study was to evaluate the sensitivity, specificity and diagnostic accuracy of contrast enhanced computed tomography (CECT) in detecting nodal metastasis in oral squamous cell carcinoma taking histopathology as gold standard. This cross sectional study comprised of n=125 diagnosed cases of oral squamous cell carcinoma. Preoperative CECT was done in each patient. Lymph nodes showing one or more features on CECT scan including ill-defined irregular bordered mass, non-enhancing mass in the nodal area greater than 1.5 cm for sub-mandibular & jugulodigastric nodes, greater than 0.8cm for retropharyngeal nodes, greater than 1.0 cm for all other nodes, grouping of 3 or more nodes in 6-15 mm area, central necrosis evidence with decrease density and/or dirty fat appearance with extra nodal spread were considered positive. At surgery lymph nodes were removed and diagnosed for oral squamous cell carcinoma metastasis on histopathology. Topographical correlation between dissected nodes and CECT scans was performed. Out of n=125 patients, n=89 (71.2%) patients were males and n=36 (28.8%) patients were females. The male to female ratio was 2.5:1. Mean age of the patients was found to be 53.61 ±16.72. Tongue was found to be the most common site of involvement with n=34 (27.2%) cases followed by buccal mucosa n=27 (21.6%) cases. It was found that the overall sensitivity of CECT scan was 77.97%, specificity 68.18%, positive predictive value (PPV) 68.66%, negative predictive value (NPV) 77.59% and the diagnostic accuracy of CECT scan was 72.8% taking histopathology as gold standard. CECT scan was found to have acceptable diagnostic accuracy and can be a helpful tool in detecting lymph node metastasis in Oral Squamous Cell Carcinoma.
Full article
International Medical Journal
Journal ID : IMJ-27-02-2020-291
Total View : 159

Abstract : We evaluate the diagnostic values of some biomarkers in detecting bacterial coinfection among 40 children with Adenovirus-related severe pneumonia. Interleukin (IL)-6, high-sensitivity C-reactive protein (hs-CRP) tests were conducted. Receiver operating characteristic (ROC) analysis was used to evaluate their diagnostic values. Study findings showed that 9 children had bacterial coinfections (22.5%). The area under the curves was 0.772, 0.696 and 0.575 for PCT, hs-CRP and IL-6, respectively. The optimal cut-off point for PCT was > 2.25 ng/ml (sensitivity 77%, specificity 40%), hs-CRP was > 51.6 mg/dl (sensitivity 50%, specificity 93%), and IL-6 was > 3.36 pg/ml (sensitivity 100%, specificity 31%).
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