International Medical Journal (ISSN:13412051)

Aim and Scope

Aim-

International Medical Journal ISSN: (13412051) is an international open-access journal publishes twelve times each year. The "International Medical Journal" is a peer-reviewed, monthly, online international research journal, which publishes original articles, research articles, review articles with top-level work from all areas of Medical Science Research and their application including Aetiology, bioengineering, biomedicine, cardiology, chiropody, ENT etc. Researchers in all Medical Science and Pharmacy fields are encouraged to contribute articles based on recent research. Journal publishes research articles and reviews within the whole field of Medical Science and Pharmacy Research, and it will continue to provide information on the latest trends and developments in this ever-expanding subject. International Medical Journal journal covers almost all disciplines of Medical Science and Pharmacy. Researchers and students of M.B.B.S, M.D., D.T.C.D., GYNE., M.S., M.Pharma, And PhD are requested to send their original research articles to International Medical Journal. Azerbaijan Medical Journal Gongcheng Kexue Yu Jishu/Advanced Engineering Science Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery Interventional Pulmonology

Scope-

International Medical Journal ISSN: (13412051) is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:

Anatomy Physiology Biochemistry Pharmacology
Pathology Forensic medicine Microbiology Community Medicine
Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology
Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases
Anaesthesia Cancer research Neurosurgery Orthopedics

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Latest Journals
International Medical Journal
Journal ID : IMJ-07-08-2021-839
Total View : 697

Abstract :

Managing perioperative pain is a challenge for the treating surgeon and anesthesiologist. Transdermal route of drug administration is a novel method to deliver drugs in a simple, non-invasive and compliant way. In this prospective, randomized, double blinded, comparative study, we intent to compare the preemptive use of transdermal Buprenorphine patches of 5 mg and 10 mg, for analgesia, post operatively in lower limb orthopedic surgeries under spinal anesthesia. The results obtained showed that the Numerical Rating scale (NRS) scores were on higher side at all periods of observation in the 5 mg group and this difference was statistically significant. The NRS scores during rest and on movement in the pre- operative period and the period just before surgery were slightly higher in 5 mg group but this difference was not statistically significant. But the 8 hours ,12 hours, 24 hours, 48-hour post-surgery NRS scores were higher in the 5 mg group and this difference was statistically significant (p<0.05) during rest and on movement. The rescue analgesia required by the 5 mg group was also higher than the 10 mg group and was statistically significant. Hence the 10 mg patch was more effective than the 5 mg patch for postoperative analgesia.

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Full article
International Medical Journal
Journal ID : IMJ-07-08-2021-838
Total View : 682

Abstract :

Hepatitis B virus (HBV) infection is a serious health problem affecting nearly 400 million people worldwide, which can lead to liver fibrosis. Mean Platelet Volume (MPV) and Platelet Distribution Width (PDW) are part of a complete blood count. High MPV and PDW values have been observed in hepatitis B patients with severe liver fibrosis. This study aimed to determine the correlation between degree of liver fibrosis with MPV and PDW in chronic hepatitis B patients. MPV and PDW data were collected from medical records of naive hepatitis B patients who underwent transient elastography (FibroScan) examination at Wahidin Sudirohusodo Hospital Makassar from January 2018 - December 2020. Degree of liver fibrosis determined by FibroScan. The statistical tests used were Pearson's correlation and ANOVA. The results were considered significant if p-value <0.05. This study included 862 subjects consisting of 62.8% male with a mean age of 39.1 ± 13.1 years. The distribution of FibroScan results were 63.1% non-fibrosis, 20.4% significant fibrosis, and 15.5 severe fibrosis. The degree of liver fibrosis has a significant positive relationship with each MPV and PDW, the higher degree of liver fibrosis is in accordance with higher MPV and PDW (each p<0.001). The highest mean of MPV and PDW were found in severe fibrosis (9.2 fl and 13.5 fl). The degree of liver fibrosis has a significant positive relationship with each MPV and PDW in chronic hepatitis B patients.

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Full article
International Medical Journal
Journal ID : IMJ-07-08-2021-837
Total View : 735

Abstract :

Amyloidosis is a group of heterogeneous diseases characterized by extracellular deposition of proteinaceous material in various organs.  Multiple dermatological manifestations of amyloidosis have been described, including nodules, papules, plaques and periorbital ecchymosis. We report a case of idiopathic primary systemic amyloidosis presenting with unusual extensive upper and lower limbs ecchymoses along with laryngeocel, lacking the classical presentation of macroglossia, waxy papules, and plaques.

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Full article
International Medical Journal
Journal ID : IMJ-07-08-2021-836
Total View : 550

Abstract :

Obesity has been linked with increased morbidity and mortality although the causes of obesity are not well understood. Its’ obvious involvement in the respiratory system causing obesity hypoventilation syndrome (OHS), obstructive sleep apnoea(OSA) and abnormal pulmonary function is well known, but how the presence of excess fat in the body is involved in the various inflammatory or other disease of the respiratory system are not clearly known. In this presentation, we further explore the mechanism involved in alterations in lung function caused by obesity. It is observed that obese individuals have increased respiratory rates, reduced tidal volumes and decreased total lung compliance. The lung volumes are usually reduced, especially expiratory reserve volume. However, in most cases, airway resistance and gas exchange seem to be relatively well preserved. Obese individuals usually have mild hypoxemia due to ventilation- perfusion imbalance in bases of lung fields possibly due to micro atelectasis. Weight loss in such individuals to a large extent may reverse these changes.

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Full article
International Medical Journal
Journal ID : IMJ-07-08-2021-835
Total View : 701

Abstract :

Tumor associated macrophages (TAMs) and COX-2 has been reported in association with tumorigenesis, invasion, angiogenesis and metastasis of non-melanoma skin cancer (NMSC). In this study, we used immunohistochemistry on a total number of 30 cases to study histomorphological spectrum and investigate density of TAMs (CD 68) within or at the periphery of tumor along with COX‐2 expression in a series of metastatic tumors of skin i.e. squamous cell carcinoma, basal cell carcinoma and sebaceous cell carcinoma. The maximum patients (33%) were seen in fifth decade with predilection of male gender (60%). The mean age (years) for basal cell carcinoma, squamous cell carcinoma and sebaceous cell carcinoma were 65.59 ± 8.02, 61.17 ± 22.95 and 55.00 ± 0 respectively. Cheek (20%) was more commonly involved site with ulcer (43%) as most common presentation. A significant statistical correlation was found with respect to lesion size (p 0.02) and sun exposure (0.027). Maximum patients were of BCC while maximum association with sun exposure and expression of TAM and COX-2 immunostaining were observed in BCC. In this study, almost 80% and all cases of NMSC simultaneously showed significant expression of COX-2 and TAM (CD 68) respectively but no statistical correlation was found between the various NMSC histological types and differentiation of squamous cell carcinoma as p value was >0.05. Conclusions: We can conclude that both COX-2 and TAM (CD 68) may play role in the development of NMSC as maximum cases showed positivity for both the markers.

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