International Medical Journal (ISSN:13412051)

Aim and Scope

Aim-

International Medical Journal ISSN: (13412051) is an international open-access journal publishes twelve times each year. The "International Medical Journal" is a peer-reviewed, monthly, online international research journal, which publishes original articles, research articles, review articles with top-level work from all areas of Medical Science Research and their application including Aetiology, bioengineering, biomedicine, cardiology, chiropody, ENT etc. Researchers in all Medical Science and Pharmacy fields are encouraged to contribute articles based on recent research. Journal publishes research articles and reviews within the whole field of Medical Science and Pharmacy Research, and it will continue to provide information on the latest trends and developments in this ever-expanding subject. International Medical Journal journal covers almost all disciplines of Medical Science and Pharmacy. Researchers and students of M.B.B.S, M.D., D.T.C.D., GYNE., M.S., M.Pharma, And PhD are requested to send their original research articles to International Medical Journal.

Scope-

International Medical Journal ISSN: (13412051) is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:

Anatomy Physiology Biochemistry Pharmacology
Pathology Forensic medicine Microbiology Community Medicine
Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology
Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases
Anaesthesia Cancer research Neurosurgery Orthopedics

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Latest Journals
International Medical Journal
Journal ID : IMJ-01-11-2019-24
Total View : 524

Abstract : The purpose of the present study were isolation of K. pneumoniae from clinical samples, determination of their antibiotic sensitivity against commonly prescribed antibiotics and evaluation of their ability to produce extended-spectrum beta-lactamase (ESBL), AmpC and Carbapenemase enzymes.The study was performed at the Department of Microbiology, Primeasia University, Banani, Dhaka-1213, Bangladesh. For isolation and identification of klebsiella, cultural characteristics on blood agar and MacConkey agar was observed along with different biochemical tests and the disc diffusion assay on Mueller-Hinton agar was done for determination of antibiotic sensitivity. Statistical analysis was done by employing Statistical Package for Social Science (SPSS Version 16) software. Total 120 sputum samples were collected of them 51 (42.5%) K. pneumoniae were identified. Sensitivity towards 15 differents antibiotics were determined by Kirby Bauer disc diffusion method. Third generation cephalosporin resistant bacteria were further analyzed to determine their extended-spectrum beta lactamases enzyme producing ability by double disc synergy test. AmpC and OXA-48 disc tests were used for detection of AmpC and Carbapenemase producer. Among 51 K. pneumoniae, 39 (76.5%), 31(60.8%), and 3(5.9%) were found ESBL, AmpC and Carbapenemase producer respectively. K. pneumoniae showed maximum sensitivity to Netilmicin (92.2%), Amikacin (90.1%), Meropenem (90.1%), Imipenem (88.2%), Ciprofloxacin (80.3%), L.
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International Medical Journal
Journal ID : IMJ-30-10-2019-17
Total View : 772

Abstract : Abstract: There are many drivers for the emergence of antimicrobial resistance among pathogens. Misuse of antibiotics constitutes a growing global public health concern. There are many reports of outbreaks caused by bacterial strains that have acquired several mechanisms of antimicrobial drug resistance. Objectives: This study tries to assess the general public’s knowledge and opinions regarding the use of antibiotics and bacterial resistance in a rural area of Minia, Egypt. Methods: All the participants had to be older than 16 years and had to participate in the survey voluntarily. A total of 386 participants answered the questionnaire, from March 2018 to June 2018. Results: Most of the participants (82%) received antibiotics treatment with a prescription. More than half of the respondents (68.7%) discontinue their therapy after the alleviation of symptoms. Half of the participants (50%) in this study repeated the same antibiotic after having the same symptoms. The major source of antibiotic prescription was from family and friends (65.8%). The most common reason for the administration of antibiotics was sore throat (67.4%). Most of the participants (75.1%) understood that the antibodies resistance is the resistance of bodies to antibiotics and so they will no longer work as well. Most of the participants (69.9%) showed high awareness and agreement towards giving fewer antibiotics to farm animals. Conclusion: Based on the results, the authors thought that the most c.
Full article
International Medical Journal
Journal ID : IMJ-30-10-2019-15
Total View : 586

Abstract : Direct acting antiviral agents will change the shape of the future of liver diseases especially in countries where hepatitis C virus (HCV) infection is the main cause of liver pathology. Sofosbuvir, an approved DAAs, has been incorporated into several IFN-free regimen. Some clinicians observed occurrence of HCC with initiation of DAA in cirrhotic patients, so, the clinical history and data of the reported HCC-developed patients need to be analyzed carefully before any conclusive comments. Aim We evaluated the efficacy and safety and searched for development of new hepatocellular carcinoma in Egyptian cirrhotic patients with chronic hepatitis C who are treated by a sofosbuvir-based regimen. Methods Treatment-naïve or treatment-experienced patients with genotype 4 HCV (+) advanced liver disease, who had been treated with Sofosbuvir- containing regimens (n = 200) were randomly assigned to receive either 24 weeks of sofosbuvir and ribavirin daily or 12 weeks of sofosbuvir, daclatasvir and ribavirin. Results SVR12 rates were 95% (114/120) with 24 weeks of sofosbuvir and ribavirin and 97.5% (78/80) with 12 weeks of sofosbuvir, daclatasvir and ribavirin therapy. The most common adverse events in both groups were headache, insomnia, diarrhea and fatigue. No patients had adverse events leading to dose modification, interruption, or discontinuation of sofosbuvir. Hepatocellular carcinoma was detected in one patient. Conclusion sofosbuvir-containing regimen is promising and safe.
Full article
International Medical Journal
Journal ID : IMJ-22-10-2019-10
Total View : 1288

Abstract : This examination was embraced to explore the appropriation of etiological specialists and antimicrobial opposition design among the blood culture-positive instances of neonatal sepsis admitted to a dimension III neonatal consideration unit in a showing medical clinic Kolkata, Eastern India for the time of 4 years (2014 – 2017). Blood culture was accomplished for all infants conceded with clinical sepsis or with positive sepsis screen via mechanized BACTEC 9050 framework. In positive cases, distinguishing proof of creature was done trailed by antimicrobial affectability testing by Kirby Bauer plate dissemination strategy utilizing Clinical Research Center Standard Organization Rules. Multi-sedate obstruction (MDR) was characterized as the nearness of protection from at any rate three of the five anti-microbial gatherings if there should arise an occurrence of gram-negative microscopic organisms. Chi-squared test was performed to test the relationship between various gatherings. Out of 4781 instances of clinical neonatal sepsis, 415 (8.68%) were culture positive. In 240 (69%) cases, the pathogens had a place with the family Enterobacteriaceae. Gram-positive cocci represent 38 (11%) instances of positive blood culture cases. Klebsiella is the preeminent irresistible operator with positive in 187(54%) of all bacterial segregates..
Full article
International Medical Journal
Journal ID : IMJ-22-10-2019-9
Total View : 1365

Abstract : Hospitalized patients accepting All Out Parenteral Sustenance (TPN) are in danger of building up a few nosocomial contaminations, and to be specific candidemia. This investigation meant to evaluate this rate in a solitary focus in Saudi Arabia and to investigate potential hazard factors. A review survey including all patients confessed to Ruler Abdulaziz College Medical clinic in Jeddah, Saudi Arabia, somewhere in the range of 2014 and 2015, and who was on TPN. One hundred and sixteen patients were incorporated into this examination. Male patients comprised (62.1%), and with a mean period of (55.6 ± 18.4) years. The occurrence of candidemia was (11.2%). TPN length was essentially longer in patients who tried positive for candidemia (26.1±21.2 days) when contrasted with the individuals who tried negative (14.2±11.7 days; P = 0.002). As to factors; a past filled with strong organ danger, or being on corticosteroids before TPN were both fundamentally connected with being sure for candidemia (P=0.004 and P=0.019, separately). Hospitalized patients accepting TPN are in danger of candidemia, particularly those on delayed TPN or those on corticosteroids. Patients on TPN ought to be overseen by a specific and devoted healthful help group..
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