: Chronic obstructive pulmonary disease (COPD) is a non-infectious disease that has become a public health problem in Indonesia. We examine the relationship between smoking risk factors, lower respiratory tract infections, leukocyte count (eosinophil, neutrophil, and lymphocyte), and thoracic rays and varying degrees of stable COPD. This study is quantitative and uses a cross-sectional research design. Samples were taken from patients with stable COPD who were treated in Sukapura Jakarta Islamic hospital. The date of the study on November 30, 2017. There were 37 patients as samples study using a total sampling technique. The data used in this research are secondary data from the COPD patient medical records. The chi-square test was employed. This test is used to identify whether or not there is a significant relationship between independent variables and a dependent variable. Statistical tests were completed using SPSS 16.0. The most prevalent COPD risk factor associated with a moderate degree of COPD was being a smoker. The degree of COPD was obtained from leukocytosis results from 13 patients. The degree of severe COPD was obtained from the results of the chest x-ray of 1 patient. The most severe degree of COPD was obtained from the high neutrophil results of 2 patients. The majority of COPD patients included moderate COPD, including more severe smokers, those who had smoked for over 30 years, and trends including bronchitis, leukocytosis, low ESR, eosinopenia, neutropenia, and lymphocytopenia.