International Medical Journal (ISSN:13412051)

Aim and Scope

Aim-

International Medical Journal ISSN: (13412051) is an international open-access journal publishes twelve times each year. The "International Medical Journal" is a peer-reviewed, monthly, online international research journal, which publishes original articles, research articles, review articles with top-level work from all areas of Medical Science Research and their application including Aetiology, bioengineering, biomedicine, cardiology, chiropody, ENT etc. Researchers in all Medical Science and Pharmacy fields are encouraged to contribute articles based on recent research. Journal publishes research articles and reviews within the whole field of Medical Science and Pharmacy Research, and it will continue to provide information on the latest trends and developments in this ever-expanding subject. International Medical Journal journal covers almost all disciplines of Medical Science and Pharmacy. Researchers and students of M.B.B.S, M.D., D.T.C.D., GYNE., M.S., M.Pharma, And PhD are requested to send their original research articles to International Medical Journal. Lizi Jiaohuan Yu Xifu/Ion Exchange and Adsorption Fa yi xue za zhi

Scope-

International Medical Journal ISSN: (13412051) is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:

Anatomy Physiology Biochemistry Pharmacology
Pathology Forensic medicine Microbiology Community Medicine
Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology
Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases
Anaesthesia Cancer research Neurosurgery Orthopedics

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Latest Journals
International Medical Journal
Journal ID : IMJ-06-10-2023-1644
Total View : 480
Title : Etiological and Medico-Legal Based Assessment of Intentional Burn: A Systematic Review
Abstract : Self-inflicted Burns also referred to as deliberate, inflicted, and non-accidental burns are frequently accompanied by mental health issues including depression, anxiety, or borderline personality disorder, and need to be treated right once to stop additional damage. The goal of this article is to determine the Current etiological factors of self-inflicted burns, further preventative approaches to lower the future incidence of intentional burns, and an evaluation of the medico-legal implications. A study of the literature was done on a few of the earlier research from different publications and databases. A digital database was looked up. Studies that were determined to be pertinent to the current goal were chosen at random. The initial examination and information that a doctor can provide are invariable of great value, not only in providing medical and psychological treatment but also providing evidence against the guilty..
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International Medical Journal
Journal ID : IMJ-23-09-2023-1641
Total View : 415
Title : Association between the workload of nurses and patients’ safety outcomes, Mogadishu. Somalia
Abstract : The nursing workload is a significant public health concern and one of the most persistent themes in health worldwide. The Insufficient nurses staffing or overworked of nurses in hospital-based care could lead severe consequences of patients' safety outcomes, such as mortality, infections, and failure to rescue, as well as decrease quality of care. No previous study has been done in Somalia in this regard. Therefore. This study aimed to determine the association between nurses' workload and patient safety outcomes at Mogadishu, Turkey's Recep Tayyip Erdogan Training and Research Hospital, Mogadishu, Somalia. The study was a cross-sectional study was conducted among registered working nurses and selected patients who were registered and admitted at Mogadishu, Somalia—Turkey's Recep Tayyip Erdogan Training and Research Hospital. The study populations were selected using simple random sampling methods, and data were analysed using multiple logistic regression analysis. A total of 360 participants were analysed. Overwhelmingly, 93 (51.7%) nurses worked between 8 and 12 hours per day in each shift on daily based. Every five nurse respondents, one worked more than 12 hours daily—63 (35%). According to the findings of this study, the majority of nurses (82.88%) were have felt stressed due to their workload. Multiple logistic regression analysis revealed the risk factors associated with patients’ safety outcomes were Urinary Trac Infection (UTI) was (AOR = 0.03 95% CI = (0.163-0.571, P = 0.001), Blood Stream Infection (BSI) (OR = 3.909, 95% CI = 2.312-6.610, P = 0.001), and patient monitoring tragedy (AOR = 0.61 95% CI = (0.031-0.199, P = 0.001). The results revealed that most nurses worked between 8 and 12 hours per day and were highly stressed due to the burden of their work. The risk factors associated with nurses' workload and patients' safety were the incidence of UTI, BSI and patient monitoring tragedy. This study emphasised that nurses' workloads directly affected patients' safety consequences. This study reported a lack of the following recommended international Labouré Standardization (ILS) guidelines in Somalia for nurses' rights and work standardisation. Also, immediate action needs to be taken by Somalia's health authorities to protect the nurse's rights..
Full article
International Medical Journal
Journal ID : IMJ-24-08-2023-1635
Total View : 414
Title : A Comparative Analysis of Hematological Parameters and Platelet Morphological Parameters in Type 2 Diabetes Mellitus Patients with and without Retinopathy
Abstract : Diabetes Mellitus (DM) is a global health concern with rising prevalence. Hyperglycemia and glucose intolerance are characteristic of DM, which includes Type 1, Type 2, gestational diabetes, and other subtypes. Type 2 Diabetes Mellitus (T2DM) is the most common form. T2DM is associated with hyperglycemia and insulin resistance. This study investigates hematological and platelet characteristics in T2DM patients with and without retinopathy, exploring potential systemic effects beyond ocular symptoms. This study compared hematological and platelet characteristics in T2DM patients with and without retinopathy to understand potential systemic hematological changes associated with retinopathy in T2DM. A cross-sectional study was conducted at DRMLIMS tertiary care hospital from April 2019 to August 2020. 300 participants with Type 2 diabetes and retinopathy were included based on a questionnaire. Data on demographics, symptoms, diabetes duration, and medication were collected. Fasting blood samples were analyzed for Hematological Parameters and Platelet Morphological Parameters. Statistical analysis was performed using IBM SPSS Statistics version 22.0. Among patients with Type 2 Diabetes Mellitus (T2DM) and retinopathy, total leukocyte count (TLC) was higher (p<0.001), while platelet morphological parameters (MPV, PDW, and P-LCR) were significantly elevated (p<0.05). MPV and PDW showed a significant association with retinopathy grade (p<0.001). MPV and PDW were associated with HbA1c levels (p<0.001). Our study emphasizes measuring hematological and platelet parameters in individuals with and without retinopathy in type 2 diabetes. These markers show potential for indicating retinopathy and require further research for better understanding and management..
Full article
International Medical Journal
Journal ID : IMJ-23-08-2023-1634
Total View : 469
Title : Computational study for predicting the effects of missense variants on PTEN protein : assessement of functional and structural impact and association with prostate cancer
Abstract : Studies on nsSNPs have demonstrated their implications in several pathologies including hereditary diseases. In cancerous diseases, several genes have been the subject of studies in search of a possible contribution, particularly in hereditary cancers such as prostate cancer. The PTEN gene is one of the candidates frequently studied in this cancer, primarily due to its crucial role in the PIK3/AKT pathway, which is one of the fundamentals signaling pathways involved in carcinogenesis. Throughout this study we employed various computational approaches to identify nsSNPs that maybe deleterious to the structure and/or function of PTEN protein and potentially contributing to diseases such as cancers. The analysis was performed by executing various valid computational tools, including : SIFT, PANTHER, ALIGN GVGD, PolyPhen.2, I.Mutant.2, Fathmm, ConSurf, Interproscan, Raptor X, SWISS-MODEL. Out of 573 variants, 148 variants were found to be deleterious after analysis by the four tools (SIFT, Polypehen2, Panther, Align GVGD). Further evaluation of these variants by the three tools consurf, Fathmm and I.Mutant allowed the identification of 97 SNPs associated with cancer and decrease the stability of the protein. Analysis of the functional domains of the protein (InterProscan tool) revealed that 86% of the variants are located in the PTP domain, of which 14 variants correspond to 7 codons situated in the active site of the protein. Protein structure property prediction by Raptor X server showed significant differences in secondary structure (SS), solvent accessibility (ACC), and disorder regions (DISO). The results of this study support the probability of a pathogenic effect of the 14 variants of the PTEN protein : I122S, H123D, C124S, C124R, C124G, C124Y, G127R , G127V, G129R, G129V, R130G, R130P, G132D, G132V. With the emergence and current prominence of personalized medicine in the care of cancer patients, in vivo studies on the variants identified in this computational study are highly opportune, in particulary in association with the other risk factors and clinicopathologic parameters of the patients..
Full article
International Medical Journal
Journal ID : IMJ-13-08-2023-1632
Total View : 436
Title : MOLECULAR CHARACTERISATION AND PHYLOGENETIC ANALYSIS OF SHEEPPOXVIRUS RPO30 GENE ISOLATES FROM MOROCCAN SHEEP
Abstract : Sheeppoxvirus (SPPV) and Goatpoxvirus (GTPV) are classified as causal agents of notifiable viral diseases. They belong to the genus Capripoxvirus (CaPV) with the Lumpy skin disease virus (LSDV). Although SPPV and GTPV have host preferences, certain strains may infect sheep and goats. Capripoxvirus (SPPV, GTPV, and LSDV) are antigenically related but genetically distinct and require molecular analysis for differentiation. In this study, the RPO30 gene from six isolates identified in Capripoxvirus outbreaks in different parts of Morocco between 2018 and 2021 were genetically and phylogenetically analysed to describe their genetic relationship. Sequential analysis revealed that the percentage of RPO30 nucleotide identity ranged from 93% to 99%, with CaPVs isolates from other countries. The constructed phylogenetic tree classified the six CaPVs detected as GTPVs. Additional analyses and alignments must be undertaken to facilitate the diagnosis and control of Sheeppox in Morocco..
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