International Medical Journal

Journal ID : IMJ-18-12-2020-703

Total View : 380

Title : Rate of Fetal Macrosomia and Its Associated Risk Factors in Pregnant Woman in a Tertiary Care Hospital.

Abstract : Macrosomia is described as a newborn with excessive birth weight. Fetal macrosomia has been defined in several different ways, including the birth weight of 4000– 4500 gm. A diagnosis of fetal macrosomia can be made only by measuring birth weight after delivery; therefore, the condition is confirmed only after delivery of the neonate. Fetal macrosomia is encountered in up to 10% of deliveries. The aim of the study is to find the rate of prevalence of fetal macrosomia and its associated risk factors in pregnant women and secondary objective is to find out the maternal and neonatal complications occurring at the time of delivery. This was a retrospective study conducted at the O&G department of Hospital Sultan Abdul Halim, Sungai Petani, Kedah, Malaysia. All the pregnant women admitted to the O&G ward were included in the study. A total of 5763 women delivered during the period of January 2020 to August 2020. Study groups include O&G patients who attended the inpatient department. Data of the patients were collected by using a pre-designed data collection form. Patient’s demographic characteristics and pregnancy data were collected from the patient’s folder in the database system. The collected data was then transferred and descriptive analysis and chi-squrare test was used to see whether there is any statistically significant association between macrosomia and risk factors, neonatal, and maternal complications. Among 5763 deliveries, 46 were macrosomic babies, all of them (100%) were Malay patients. The prevalence of macrosomic babies was less than 1%, which is 0.798%. Diabetes, hypertension, obesity, parity, and previous macrosomia are found to be the maternal risk factors of macrosomia. The highest percentage of maternal complications was 37% having perineal tears, followed by anemia in pregnancy (21.7%), postpartum hemorrhage (2.2%), and uterine fibroid (2.2%). Most of the babies had hypoglycemia (8.7%) and pneumonia (6.5%). Other neonatal complications are such as clavicle fracture (4.3%), incomplete Moro reflex (4.3%), patent ductus arteriosus (4.3%), and undescended testes (4.3%). The prevalence of macrosomic babies in this certain tertiary care center is less. However, extra care needs to be taken as there are maternal and neonatal complications that can be serious. The advice of doctors on the mode of delivery for macrosomic mother need to be taken to ensure safe delivery..
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International Medical Journal

Journal ID : IMJ-17-12-2020-702

Total View : 409

Title : The Relationship of Leptin, Interferon-γ, Interleukin-17, Interleukin-6 and Interleukin-10 with Obesity and Hypertension

Abstract : The relationship between cytokines and dyslipidemia, obesity and hypertension are of great importance in the pathophysiology and progression of metabolic syndrome (MetS). This study aims to investigate the association of five cytokines with the accumulation of metabolic disorders including; dyslipidemia, obesity and hypertension. A total of 50 healthy individuals and 100 patients with MetS have been enrolled. Based on MetS biomarkers, eligible patients were divided into two groups; group 1; obese + dyslipidemic patients and group 2; obese + dyslipidemic and hypertensive patients. The results showed a marked increase in the level of leptin, interferon-γ (IFN-γ), interleukin-17 (IL-17) as well as expression of interleukin-6, (IL-6), but a decrease in the expression of interleukin-10 (IL-10) level was recorded in both MetS groups relative to healthy controls. Additionally, the results revealed a higher frequency of the IL-17A/A homozygote polymorphism in MetS patients. Among group 1, the recorded values of MetS patients showed a positive correlation between leptin with obesity and IL-17 and a negative correlation between IL-10 and obesity. Regarding group 2, leptin recorded a positive correlation with dyslipidemia, while IL-17 exhibited a positive correlation with blood pressure, obesity, and dyslipidemia. On the other hand, IL-10 observed a negative correlation with blood pressure, obesity, and dyslipidemia. Therefore, leptin, IFN-γ, IL-17, IL-6, and IL-10 were associated with the MerS biomarkers and linked to the pathophysiology mechanisms of MetS component pathophysiology and development. Notably, understanding of these pathways would help the development of anti-inflammation therapeutic strategies..
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International Medical Journal

Journal ID : IMJ-15-12-2020-701

Total View : 442

Title : Body Image Perception and Depressive Symptoms among Bahraini Adolescents: A gender-based comparison (cross-sectional study)

Abstract : Adolescence is a special age with great physical changes; it is also an important period for body image and self-concept development. The association between obesity and psychological health among adolescents has been researched extensively, but the epidemiologic results are inconsistent. The aim of this study is to evaluate how the body image perception is contributing to depressive symptoms amongst Bahraini adolescents. A cross sectional study conducted among 460 adolescent aged 10-19 years attending four primary health care centers representing the four governorates of Bahrain during February and March 2019. Self-filled questionnaire was given to adolescents after identifying them in the reception. Demographic, body image and mental health data were included. A total of 460 adolescents participated in the study, of which 217 (47.2%) were males and 243 (52.7%) were females. Although most of the adolescents (47.8%) described their weight as “right” weight, but significantly higher proportion of females (45.7%) think that they are overweight in comparison to males (30%). Females reported feeling sad or depressed (37.4%) significantly more than males (23%). Reporting depression was much higher among overweight females (54.1%) in comparison to overweight males (23.1%) The results of this study indicated that depressive symptoms among Bahraini adolescents are associated with perceived body image in both genders, but it is significantly more among females..
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International Medical Journal

Journal ID : IMJ-14-12-2020-700

Total View : 404

Title : The Effectiveness of Elderly School Integration in Bina Keluarga Lansia Group (ESI-BKL) to Achieve Seven Dimensions of Robust Elderly

Abstract : The number of the elderly population in Yogyakarta Province, Indonesia, is higher compare to other cities in Indonesia. Therefore, supports from various sectors are required, including supports from the government, private sector, and community to improve the quality of life among elderly. An Elderly School Integration in Bina Keluarga Lansia (ESI-BKL) is one of the innovative interventions that have a strategic role in achieving seven dimensions of robust elderly. Respondents in this study are pre-elderly and elderly who are involved in ESI-BKL program for one year. The study design was a quasi-experimental study without control group design. The sampling technique in this study was purposive sampling. Statistical analysis performed in this study was the Wilcoxon Signed-rank test. The results of the study show there are significant differences in the intellectual, social, spiritual, environmental, vocational, and emotional dimensions before and after following ESI-BKL (p-value < 0.05). Moreover, there are no differences in the physical dimension before and after following the ESI-BKL (p-value=0.377). However, the robustness of the elderly can be measured through the indicators of 7-dimension of robust elderly. The measurement results show very significant differences in 5 dimensions, namely intellectual, social, spiritual, environmental, and emotional dimensions. In contrast, there are no significant differences in Physical and Vocational Dimensions..
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International Medical Journal

Journal ID : IMJ-12-12-2020-699

Total View : 370

Title : Correlation between Transepidermal Water Loss with Proinflammatory Cytokines in Non-Aging and Aging Group

Abstract : Aging is a complex process and make progressive loss of functional capacity of organ such as skin. Trans epidermal water loss represent changes in skin permeability which happen in aging. There is an imbalance of immune system in aging. It can cause condition called inflammaging. Proinflammatory cytokines such as IL-6 and TNF-α were elevated in skin aging. Purpose: This study aims to find correlation between TEWL and proinflammatory cytokines in non-aging and aging Methods: This research is an analytic observational study with cross sectional design. The IL-6 and TNF-α level was measured by using sandwich ELISA technique. TEWL was measured by Tewa meter. Results: The mean value of IL-6 and TNF-α in both non-aging and aging group showed no significantly difference. The TEWL in aging and non-aging group showed no statistically significant difference with and IL-6 and TNF-α. Conclusion: There was no significant relationship between TEWL and proinflammatory cytokines in non-aging and aging group..
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International Medical Journal

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Submission Deadline ( Vol 30 , Issue 06 )
20 Jun 2023

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Publish On ( Vol 30 , Issue 05 )
31 May 2023