International Medical Journal (ISSN:13412051)

Aim and Scope

Aim-

International Medical Journal ISSN: (13412051) is an international open-access journal publishes twelve times each year. The "International Medical Journal" is a peer-reviewed, monthly, online international research journal, which publishes original articles, research articles, review articles with top-level work from all areas of Medical Science Research and their application including Aetiology, bioengineering, biomedicine, cardiology, chiropody, ENT etc. Researchers in all Medical Science and Pharmacy fields are encouraged to contribute articles based on recent research. Journal publishes research articles and reviews within the whole field of Medical Science and Pharmacy Research, and it will continue to provide information on the latest trends and developments in this ever-expanding subject. International Medical Journal journal covers almost all disciplines of Medical Science and Pharmacy. Researchers and students of M.B.B.S, M.D., D.T.C.D., GYNE., M.S., M.Pharma, And PhD are requested to send their original research articles to International Medical Journal.

Scope-

International Medical Journal ISSN: (13412051) is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:

Anatomy Physiology Biochemistry Pharmacology
Pathology Forensic medicine Microbiology Community Medicine
Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology
Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases AMA, Agricultural Mechanization in Asia, Africa and Latin America Teikyo Medical Journal Journal of the Mine Ventilation Society of South Africa
Anaesthesia Cancer research Neurosurgery Orthopedics

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Latest Journals
International Medical Journal
Journal ID : IMJ-20-06-2020-518
Total View : 356

Abstract : Diabetic nephropathy is a common complication of diabetes mellitus type2. The mechanism involved is include changes in blood vessel that supply peripheral nerves and metabolic disorder such as increased or activation polyol pathway and non-enzymatic glycation. This study was aimed to Evaluate Fibroblast growth factor 23 (FGF23) in kidney damage susceptibility Correlation of theses markers with disease progression in Diabetic nephropathy patients. This case-control study was carried out on patients who attended multi teaching centers (Baghdad Teaching Hospital and Ghazi Al Harriry Teaching Hospital) for the period from April 2018 to June 2019. The subject which enrolled in this study was 90. The patients were 90 (55 males and 35 females), whose ages ranged from (50 to 82) years. They diagnosed as having CKD and DM based on previous medical reports, laboratory tests and clinical examination by consultant nephrologist. The results of those patients were compared with (30) DM only persons whose ages ranged from (50-82) years (17 males and 13 females), 30 CKD and DM with normal microalbumuria whose ages ranged from (50-82) years (18 males and 12 females), as a control group and 30 DM, CKD and abnormal microalbumuria. The following tests were applied for all the patients and the control groups; they were evaluated by different laboratory methods: Serum fibroblast growth factor 23 Serum urea, Serum creatinine, and Albumin / creatinine ratio. The level of fasting blood sugar (F.BS) show (P<0.05) significance difference among the three groups with the higher level in the DMT2 with macroalbumin compared with the two other groups DMT2 with microalbumin and the DMT2 without albumin nephropathy. Control Correlation tests between FGF23 and (BMI Kg/m2, Urea mg/dl, Creatinine mg/dl and Alb:creatinine mg/g ) among DMT2 and without nephropathy (Control) , DMT2 with micro-albumin and DMT2 with macro-albumin show significant at baseline. From this study, it can conclude that: the measurement of serum FGF23 was of clinical value in assessment of renal damage that associated with DMT2 patients between the baseline time and after 6 months.
Full article
International Medical Journal
Journal ID : IMJ-19-06-2020-517
Total View : 301

Abstract : The incidence of hip fractures in patients with a history of cancer is expected to increase, whether the fracture is pathologic or not. This study sought to answer two decision points: (1) What is the appropriate imaging modality to determine if the fracture is pathologic? (2) Is osteosynthesis (OS) an appropriate technique in the management of femoral neck fractures in patients with a history of cancer? We did a retrospective review of patients presenting with femoral neck fractures that underwent OS or hemiarthroplasty (HA) at a single oncologic referral center. 127 patients were identified, 109 underwent HA and 18 underwent OS. Comparison of the imaging to the histologic analysis was performed to determine the accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the various imaging modalities. Analysis of radiographic imaging demonstrated the addition of advanced imaging improved the accuracy, sensitivity, specificity, PPV, and NPV compared to radiographs alone. Both HA and OS offered durable reconstructive options. Radiographs without advanced imaging for comparison are incorrect 26% of the time; advanced imaging improves the accuracy. Osteosynthesis is a durable reconstructive option in patients with a history of cancer without an underlying pathologic fracture.
Full article
International Medical Journal
Journal ID : IMJ-19-06-2020-516
Total View : 330

Abstract : Septic arthritis is a serious condition that can lead to rapid destruction of joint if it is not rapidly diagnosed and treated appropriately. The reported annual incidence is 10 in 100 000 although this increases to 70 in 100 000 in those with risk factors for developing septic arthritis mainly rheumatoid arthritis and immune-compromised patients. The aim of this study is to examine the sensitivity and specificity, and thus the clinical usefulness, of gram stain results. Single centre, retrospective case series. All joint aspirates over a three-year period from May 2015 to April 2018 were reviewed. The gram stain and final culture results noted. 830 samples were included from both native and replaced joints. Native joints accounted for a total of 701 cases (84%) of the aspirates, whilst those obtained from prosthetic joints 129 (16%). In 74 (9%) cases there was a discrepancy between the gram stain and culture results. The sensitivity of the gram stain in this case series is 22% and the specificity of the test is 99.6%. The clinician should have a low threshold for overlooking a negative gram stain result and place greater emphases on the clinical findings in conjunction with biochemical markers.
Full article
International Medical Journal
Journal ID : IMJ-18-06-2020-515
Total View : 328

Abstract : Curcumin, the essential constituent of Curcuma or turmeric, is used widely in many international cuisines. It is known for its pharmacological properties in relatively non-toxic doses. It has been used as probiotics or prebiotics as it has proven medicinal properties since its recognition in 1953. It enhances the overall health of human being by activating or improving the normal micro flora in the colon. This study aimed to investigate the antimicrobial effect of turmeric extract against some species of pathogenic E. coli bacteria hosting surgeries sites and wounds in vitro. 35 samples (swabs) from wounds or surgery sites were collected. The samples were cultured and found bacteria species were isolated and diagnosed. E. coli subtype O157:H7 was isolated form one of the samples and ethanolic Curcumin extract has applied with different concentrations to measure its antimicrobial activity against these subtypes, comparing that to other E. coli subtypes which were collected form stool samples. E. coli O157:H7 showed high resistance to ethanolic curcumin extract with all concentrations. Other subtypes of E. coli where proportionally sensitive to curcumin concentrations. The antimicrobial activity of Turmeric was not strong enough to eradicate E. coli subtype O157:H7. Higher concentrations or other additional factors along with curcumin might be required to enhance its antimicrobial activity.
Full article
International Medical Journal
Journal ID : IMJ-16-06-2020-508
Total View : 360

Abstract : Left ventricular dysfunction (LVD) is an important complication of coronary artery disease (CAD) and represents a powerful determinant of survival. the purpose of the current study was to assess scar tissue for patient with old myocardial infarction and LV systolic dysfunction by speckle tracking longitudinal strain using regional and global longitudinal strain and to compare it with late enhancement by CMR which is the gold standard method for assessment of scar transmurality, scar transmurality was the predictor of myocardial viability, the current study defined regional longitudinal strain cutoff value that discriminated between viable and non-viable myocardium. Methods: Thirty-eight patients with old myocardial infarction and LV systolic dysfunction from AL-Najaf cardiac center and AL-Nasirya cardiac center underwent transthoracic echocardiography to measure global and segmental (regional) longitudinal LV strain using two-dimensional speckle tracking and cine MRI followed by contrast-enhanced MRI to assess segmental LV function and the segmental/global (transmural) extent of scar tissue. The optimal cutoff value for regional strain to discriminate between segments with viable myocardium and segments with transmural scar was also determined. Results: A good correlation was found between global LV strain and the global extent of scar tissue on contrast-enhanced MRI (R= 0.518, n = 38, p = 0.001.). The mean segmental strain in segments with a scar score of 3 was -6.33% ± 2.28%, and for segments with a scar score of 4 was -2.67% ± 3.69%. A strain value of the cutoff value of segmental strain was calculated using (ROC curve) analysis, and it was found to be -7.5% discriminated between segments with viable myocardium and segments with transmural scar tissue on contrast-enhanced MRI with a sensitivity of 91.5% and specificity of 89.7% Conclusion: global and regional longitudinal strain measured with two-dimensional speckle tracking miscorrelated with the global and regional extent of scar transmurality assessed by contrast enhanced MRI. A cutoff value of -7.5% for regional strain discriminated between segments with viable myocardium and those with transmural scar tissue on contrast-enhanced MRI with a sensitivity of 91.5% and specificity of 89.7%.
Full article

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