International Medical Journal (ISSN:13412051)

Aim and Scope

Aim-

International Medical Journal ISSN: (13412051) is an international open-access journal publishes twelve times each year. The "International Medical Journal" is a peer-reviewed, monthly, online international research journal, which publishes original articles, research articles, review articles with top-level work from all areas of Medical Science Research and their application including Aetiology, bioengineering, biomedicine, cardiology, chiropody, ENT etc. Researchers in all Medical Science and Pharmacy fields are encouraged to contribute articles based on recent research. Journal publishes research articles and reviews within the whole field of Medical Science and Pharmacy Research, and it will continue to provide information on the latest trends and developments in this ever-expanding subject. International Medical Journal journal covers almost all disciplines of Medical Science and Pharmacy. Researchers and students of M.B.B.S, M.D., D.T.C.D., GYNE., M.S., M.Pharma, And PhD are requested to send their original research articles to International Medical Journal.

Scope-

International Medical Journal ISSN: (13412051) is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:

Anatomy Physiology Biochemistry Pharmacology
Pathology Forensic medicine Microbiology Community Medicine
Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology
Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases
Anaesthesia Cancer research Neurosurgery Orthopedics

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Latest Journals
International Medical Journal
Journal ID : IMJ-27-09-2022-1546
Total View : 470

Abstract : Perceived threat is recognised as one of the individual's cognitive assessments toward the likelihood of a danger affecting them and how bad it will be if it does. Additionally, coping strategies are a specific effort, that people employ to master, tolerate, reduce or minimize stressful events. Due to the massive impact of the recent COVID-19 global pandemic, this study aims to explore the perceived threat and coping strategies adopted by Malaysian nurses in facing COVID-19 infections. A cross-sectional study was conducted through an online form involving 319 randomly selected nurses from a teaching hospital on the east coast of Pahang, Malaysia. The perceived threat was measured using the 5-item Brief Illness questionnaire (BIPQ5), while the coping mechanism was measured using the Brief-COPE (Coping Orientation to Problems Experienced) questionnaire. Univariate and multiple linear regression was applied to assess the association between perceived threats and coping strategies adopted toward COVID-19. Perceived threat under the domain of timeliness has the highest mean score of 7.4 ± 2.1 while the lowest was under the domain of identity with a score of 4.8 ± 2.6. For coping strategies, acceptance is the most adopted strategy with a mean score of 5.7 ± 1.4 while religion is the least adopted strategy with a score of 3.5 ± 1.4. Multiple linear regression showed significant positive correlations between the perceived threat of consequences, timeliness and emotional domain with coping strategies by denial, emotional support, instrumental support, behavioural disengagement and religion among the respondents. This study showed that there is a significant positive correlation between perceived threat towards COVID-19 with coping strategies adopted by nurses in this study with timeliness being perceived as the highest threat and acceptance being the coping strategy used most by them. Therefore, any intervention activities focusing on COVID-19 which targeted this population should take into consideration of the factors mentioned to ensure its effectiveness..
Full article
International Medical Journal
Journal ID : IMJ-23-09-2022-1545
Total View : 405

Abstract : Sepsis is characterized by severe redox imbalance. Glutathione plays a major role in cellular defenses against oxidative and nitrosative stress. This review proposes a critical analysis of available data on potential factors affecting glutathione synthesis in sepsis. Glutathione is synthesized from its constituent amino acids—glutamate, cysteine, and glycine. Cysteine availability and the activity of the enzyme glutamate cysteine ligase are rate-limiting for glutathione synthesis. Neutrophils have a dual role in sepsis—defending against infection and mediating organ failure. Because glutathione (GSH) is lower in sepsis, the hypothesis that GSH depletion might impair the migratory response of neutrophils to infection. GSH depletion inhibits neutrophil infiltration, increases bacterial colonies. Conversely, the GSH and its precursor N-acetyl-L-cysteine augments neutrophil infiltration, decreases bacterial colonies and improves survival. Thus, migration of neutrophils to a site of infection and to a distant site is differently regulated, and optimal GSH levels are important for an efficient response to sepsis..
Full article
International Medical Journal
Journal ID : IMJ-21-09-2022-1542
Total View : 476

Abstract : COVID-19 pandemic has resulted in a myriad of the diseases. It has a negative psychological impact. It has affected the general population worldwide, putting additional strain on health-care professionals. Since COVID-19 was declared as a public health emergency, the levels of anxiety, depression and other mental health problems have been ominously rising. The students' mental health was tested using structured questionnaires. Seven hundred and fifty students belonging to I, II, III and final year MBBS batches were enrolled in the study, out of which 590 students completed the questionnaires. Questionnaires for measurement of psychological morbidity included the Perceived Stress Scale (PSS-4), Patient Health Questionnaire (PHQ-9) and Generalized Anxiety Disorder questionnaire (GAD-7). An analysis of descriptive statistics was conducted to illustrate the Socio-demographic and other selected variables. Correlational analysis was done using linear correlation analysis for continuous variables and logistic regression analysis for categorical variable. Students with minimal symptoms of depression was 35%, whereas the proportion of students with mild, moderate, moderately severe, and severe depression was 35.3%%, 14.7%, 11.4%, and 3.6%, respectively. Around 45% of the students had minimal symptoms of anxiety, whereas the proportions of students with minimal, mild, moderate, and severe anxiety were 44.2%, 30.3%, 16.4%, and 9.0%, respectively. A quarter (24%) students were under stress as their PSS score was >6. The present study results concluded that first year medical students are found to suffer from higher levels of stress, anxiety and depression, with majority of male students suffering from stress, whereas female students had greater depression and anxiety levels during COVID-19. Student mentoring, which includes academic, psychic, and social counseling, may aid in the prediction and management of stress, as well as the improvement of student performance..
Full article
International Medical Journal
Journal ID : IMJ-20-09-2022-1541
Total View : 368

Abstract : Midline approach for spinal anaesthesia is the most commonly used technique in practice compared to paramedian or lateral approach. A study was carried out in 50 patients undergoing LSCS of which 25 patients were given midline prick whereas other 25 were induced by giving paramedian prick for spinal anaesthesia. The results of better technique of induction was decided on basis of: Accuracy of getting through subarachnoid space without failure. Complaints of PDPH. Complaints of post dural puncture backache. Damage to spinal needle. Haemorrhagic tap. To study whether spinal anaesthesia through classic midline prick is better than paramedian approach in patients undergoing LSCS. A prospective randomised study was carried out in 50 pregnant females with maximum gravida score of 2 and all patients were divided in 2 groups of 25 each. The present study showed significant decrease in incidence of PDPH, post dural puncture backache, attempt to reach subarachnoid space and damage to spinal needle through paramedian approach. Spinal anaesthesia through lateral/ paramedian approach is better than classical midline approach..
Full article
International Medical Journal
Journal ID : IMJ-20-09-2022-1540
Total View : 456

Abstract : Anaesthesia techniques generally involved in lower limb orthopedics surgeries are central neuraxial blockade techniques. Central neuraxial blockade usually achieved with either spinal anaesthesia, epidural anaesthesia or combined spinal anaesthesia. Proximal femur nailing is most commonly done under spinal anaesthesia. Spinal anaesthesia is most frequently associated with hypotension. The current study compares the use of Phenylephrine and Mephentermine in managing hypotension after subarachnoid blockade, and its efficacy in maintaining patient’s blood pressure to normal. A randomized, prospective study over 100 patients mostly adults both male and female who have given spinal anaesthesia for proximal femur nailing are selected. They are grouped into first 50 of group X who have given Phenyephrine and second 50 of group Y who have given Mephentermine. During study, number of allequate doses of drug and other side effects of individual drug were documented. Results were documented with the help of student’s paired t test and Chi square test. 33 hypotensive events occurred in Mephentermine group and 44 hypotensive events occurred in Phenylephrine group. Mean heart rate in Phenylephrine group was lower as compared to Mephentermine group. Mephentermine is more effective as compared to Phenylephrine in treating hypotension after spinal anaesthesia also have less recurrence rate..
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