International Medical Journal (ISSN:13412051)

Aim and Scope

Aim-

International Medical Journal ISSN: (13412051) is an international open-access journal publishes twelve times each year. The "International Medical Journal" is a peer-reviewed, monthly, online international research journal, which publishes original articles, research articles, review articles with top-level work from all areas of Medical Science Research and their application including Aetiology, bioengineering, biomedicine, cardiology, chiropody, ENT etc. Researchers in all Medical Science and Pharmacy fields are encouraged to contribute articles based on recent research. Journal publishes research articles and reviews within the whole field of Medical Science and Pharmacy Research, and it will continue to provide information on the latest trends and developments in this ever-expanding subject. International Medical Journal journal covers almost all disciplines of Medical Science and Pharmacy. Researchers and students of M.B.B.S, M.D., D.T.C.D., GYNE., M.S., M.Pharma, And PhD are requested to send their original research articles to International Medical Journal.

Scope-

International Medical Journal ISSN: (13412051) is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:

Anatomy Physiology Biochemistry Pharmacology
Pathology Forensic medicine Microbiology Community Medicine
Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology
Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases
Anaesthesia Cancer research Neurosurgery Orthopedics

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Latest Journals
International Medical Journal
Journal ID : IMJ-12-12-2020-699
Total View : 364

Abstract : Aging is a complex process and make progressive loss of functional capacity of organ such as skin. Trans epidermal water loss represent changes in skin permeability which happen in aging. There is an imbalance of immune system in aging. It can cause condition called inflammaging. Proinflammatory cytokines such as IL-6 and TNF-α were elevated in skin aging. Purpose: This study aims to find correlation between TEWL and proinflammatory cytokines in non-aging and aging Methods: This research is an analytic observational study with cross sectional design. The IL-6 and TNF-α level was measured by using sandwich ELISA technique. TEWL was measured by Tewa meter. Results: The mean value of IL-6 and TNF-α in both non-aging and aging group showed no significantly difference. The TEWL in aging and non-aging group showed no statistically significant difference with and IL-6 and TNF-α. Conclusion: There was no significant relationship between TEWL and proinflammatory cytokines in non-aging and aging group..
Full article
International Medical Journal
Journal ID : IMJ-10-12-2020-697
Total View : 406

Abstract : A 34-year-old man was referred to the oncology surgeons at dr. Kariadi General Hospital with a left-sided inguinal lump 3 months ago, initially 1,5x1x1.5 after 3 days became 3.5x3x2.5 cm, with tenderness, reddish colour around the lump. Then the patient came to the general surgeon at the district hospital, he was examined and performed a surgical removal and anatomic pathology examination which resulted metastasic melanoma. The patient had a history of tattoos in the upper and lower extremities since 10 years ago. After immunohistochemically evaluation at dr. Kariadi General Hospital, the result showing that it was reactive Para cortical hyperplasia expressed by dermatopathic lymphadenitis which was caused by tattoo pigmentation. After the lump removal from the inguinal region by excision surgeon at district hospital, the patient had no other complaints and had normal activities. Since the result of immunohistochemically evaluation was not metastatic melanoma, the patient was given antibiotics and anti- inflammatory..
Full article
International Medical Journal
Journal ID : IMJ-10-12-2020-695
Total View : 397

Abstract : The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7) divides hypertensive crisis into hypertensive emergency and hypertensive urgency. Hypertensive urgency is a severe elevation in blood pressure without progressive target organ damage. The drugs, labetalol and hydralazine are usually administered for hypertensive urgency in emergency room, but a head to head comparison on efficacy of each drug has not been reported so far. In this study, efficacy of labetalol and hydralazine compared along with requirement of second dose of each drug in patients presenting to emergency room with hypertensive urgency. A prospective observational study was conducted in 100 patients, presented with hypertensive urgency in emergency room during the time period from August 2019 to July 2020, after fulfilling both inclusion and exclusion criteria. Efficacy of both drugs were compared by measuring systolic blood pressure, that is one hour after administering each drug. Percentage of decrease in systolic BP after administering labetalol was 18.98± 9.55% and that of hydralazine was 21.32± 8.08% (P value=0.039). Hence this study revealed that hydralazine is more efficacious than labetalol in systolic BP reduction. Second dose required for 15(28.3%) patients in labetalol group and that of hydralazine was only 10(21.3%) (P value=0.418) The result of the study shows that, both hydralazine and labetalol are effective (JNC-7 guidelines) and safe in hypertensive urgency. But on comparison, it is found that hydralazine is having an edge over labetalol in treating hypertensive urgency..
Full article
International Medical Journal
Journal ID : IMJ-10-12-2020-694
Total View : 412

Abstract : Psoriasis is a genetically determined inflammatory and proliferative disease of the skin characterized by hyper-proliferation, abnormal differentiation, and inflammatory infiltration in the epidermis and dermis. This chronic papulo-squamous disorder has affected 1-2% of the world population in all geographic areas. It has several morphological variants and identifying the subtype based on histopathology is of utmost importance for better patient care. In various clinical set-ups, immunohistochemistry has evolved over the years and is often used to confirm the diagnosis. The purpose of this study was to analyze various histopathological features of psoriatic biopsies, correlate these features with the clinical findings and study the expression of a proliferative marker Ki-67 using immunohistochemically methods. The prospective study included 50 clinically diagnosed cases of psoriasis and 10 controls with normal breast skin for the duration of two years (2018-2020). Routine histopathology and immunohistochemistry using Ki-67 marker were performed and results obtained from the final data were analyzed in the form of percentages and tables. The typical histopathological features of psoriasis were observed in most of the cases and they correlated with the clinical presentation. Majority of the cases showed mild Ki-67 expression and the mean Ki-67 values decreased as the disease progressed. Also the mean Ki-67 of all the psoriatic patients was higher in comparison to the mean in controls and this difference was statistically significant. Ki-67 is a good diagnostic and prognostic marker showing higher expression in psoriatic disease and can be used for a definitive diagnosis of psoriasis..
Full article
International Medical Journal
Journal ID : IMJ-10-12-2020-693
Total View : 383

Abstract : Blood transfusion is one of the most common procedure in hospitals to assist in saving millions of lives each year. However, their use is often associated with untoward effects causing Adverse Transfusion reactions (ATR). This study aims to collect and analyze reports of unexpected events or reactions in blood and blood product recipients in a secondary care hospital. ATRs were monitored in recipients of blood or blood products in a 150-bedded hospital through a prospective observational study over a period of eight months. The severity of ATR was determined by using a grading scale from 1 (mild) to 5 (death). Imputability score was applied to find the likelihood that the transfusion caused the reaction. Descriptive statistics were applied to present data in number and percentages. The incidence rate of ATRs was calculated by taking number of a particular ATR as the numerator of the total number of transfusions. Analysis comprised of 165 transfusions comprising whole blood (100; 66.66%), PRBC (48; 29.09%), platelets (9; 4.84%), and FFP (8; 4.84%), of these, majority was indicated in cardiac (42; 24.45%), orthopedic (34; 20.64%), and renal system disorders (28; 16.96%). Majority of ATRs were evidenced for whole blood (55%) followed by PRBC (52%). Most of the reactions were AHTR (23.64%), febrile (17.58%), and allergic (10.91%) in nature. Majority of reactions were acute, no serious (Grade 1 = 50.91%; Grade 2 = 24.24%) and probable (35.15%) to transfusion while only 2 reactions (1.21%) were categorized as certain. Clerical errors were identified in 98 (59.33%) transfusions. Majority of ATRs were acute, nonserious, mildly severe, and probably linked with the suspected blood component. A high number of clerical errors indicated a need for a system to minimize human errors to reduce the risk of transfusion-related untoward effects..
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