International Medical Journal

Journal ID : IMJ-30-10-2019-17

Total View : 773

Title : The Concept of Antibiotic Resistance among the Rural Population

Abstract : Abstract: There are many drivers for the emergence of antimicrobial resistance among pathogens. Misuse of antibiotics constitutes a growing global public health concern. There are many reports of outbreaks caused by bacterial strains that have acquired several mechanisms of antimicrobial drug resistance. Objectives: This study tries to assess the general public’s knowledge and opinions regarding the use of antibiotics and bacterial resistance in a rural area of Minia, Egypt. Methods: All the participants had to be older than 16 years and had to participate in the survey voluntarily. A total of 386 participants answered the questionnaire, from March 2018 to June 2018. Results: Most of the participants (82%) received antibiotics treatment with a prescription. More than half of the respondents (68.7%) discontinue their therapy after the alleviation of symptoms. Half of the participants (50%) in this study repeated the same antibiotic after having the same symptoms. The major source of antibiotic prescription was from family and friends (65.8%). The most common reason for the administration of antibiotics was sore throat (67.4%). Most of the participants (75.1%) understood that the antibodies resistance is the resistance of bodies to antibiotics and so they will no longer work as well. Most of the participants (69.9%) showed high awareness and agreement towards giving fewer antibiotics to farm animals. Conclusion: Based on the results, the authors thought that the most c.
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International Medical Journal

Journal ID : IMJ-30-10-2019-15

Total View : 598

Title : Treatment outcome of sofosbuvir-based regimen in cirrhotic patients with hepatitis C genotype 4

Abstract : Direct acting antiviral agents will change the shape of the future of liver diseases especially in countries where hepatitis C virus (HCV) infection is the main cause of liver pathology. Sofosbuvir, an approved DAAs, has been incorporated into several IFN-free regimen. Some clinicians observed occurrence of HCC with initiation of DAA in cirrhotic patients, so, the clinical history and data of the reported HCC-developed patients need to be analyzed carefully before any conclusive comments. Aim We evaluated the efficacy and safety and searched for development of new hepatocellular carcinoma in Egyptian cirrhotic patients with chronic hepatitis C who are treated by a sofosbuvir-based regimen. Methods Treatment-naïve or treatment-experienced patients with genotype 4 HCV (+) advanced liver disease, who had been treated with Sofosbuvir- containing regimens (n = 200) were randomly assigned to receive either 24 weeks of sofosbuvir and ribavirin daily or 12 weeks of sofosbuvir, daclatasvir and ribavirin. Results SVR12 rates were 95% (114/120) with 24 weeks of sofosbuvir and ribavirin and 97.5% (78/80) with 12 weeks of sofosbuvir, daclatasvir and ribavirin therapy. The most common adverse events in both groups were headache, insomnia, diarrhea and fatigue. No patients had adverse events leading to dose modification, interruption, or discontinuation of sofosbuvir. Hepatocellular carcinoma was detected in one patient. Conclusion sofosbuvir-containing regimen is promising and safe.
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International Medical Journal

Journal ID : IMJ-22-10-2019-10

Total View : 1295

Title : Bacterial Confines of Neonatal Sepsis and Anti-Infection Opposition Example in A Dimension III Neonatal Emergency Unit Eastern India: A 4 Years Report

Abstract : This examination was embraced to explore the appropriation of etiological specialists and antimicrobial opposition design among the blood culture-positive instances of neonatal sepsis admitted to a dimension III neonatal consideration unit in a showing medical clinic Kolkata, Eastern India for the time of 4 years (2014 – 2017). Blood culture was accomplished for all infants conceded with clinical sepsis or with positive sepsis screen via mechanized BACTEC 9050 framework. In positive cases, distinguishing proof of creature was done trailed by antimicrobial affectability testing by Kirby Bauer plate dissemination strategy utilizing Clinical Research Center Standard Organization Rules. Multi-sedate obstruction (MDR) was characterized as the nearness of protection from at any rate three of the five anti-microbial gatherings if there should arise an occurrence of gram-negative microscopic organisms. Chi-squared test was performed to test the relationship between various gatherings. Out of 4781 instances of clinical neonatal sepsis, 415 (8.68%) were culture positive. In 240 (69%) cases, the pathogens had a place with the family Enterobacteriaceae. Gram-positive cocci represent 38 (11%) instances of positive blood culture cases. Klebsiella is the preeminent irresistible operator with positive in 187(54%) of all bacterial segregates..
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International Medical Journal

Journal ID : IMJ-22-10-2019-9

Total View : 1370

Title : THE RATE OF CANDIDEMIA AMONG PATIENTS GETTING COMPLETE PARENTERAL NOURISHMENT (TPN): A SOLITARY CENTER EXAMINATION

Abstract : Hospitalized patients accepting All Out Parenteral Sustenance (TPN) are in danger of building up a few nosocomial contaminations, and to be specific candidemia. This investigation meant to evaluate this rate in a solitary focus in Saudi Arabia and to investigate potential hazard factors. A review survey including all patients confessed to Ruler Abdulaziz College Medical clinic in Jeddah, Saudi Arabia, somewhere in the range of 2014 and 2015, and who was on TPN. One hundred and sixteen patients were incorporated into this examination. Male patients comprised (62.1%), and with a mean period of (55.6 ± 18.4) years. The occurrence of candidemia was (11.2%). TPN length was essentially longer in patients who tried positive for candidemia (26.1±21.2 days) when contrasted with the individuals who tried negative (14.2±11.7 days; P = 0.002). As to factors; a past filled with strong organ danger, or being on corticosteroids before TPN were both fundamentally connected with being sure for candidemia (P=0.004 and P=0.019, separately). Hospitalized patients accepting TPN are in danger of candidemia, particularly those on delayed TPN or those on corticosteroids. Patients on TPN ought to be overseen by a specific and devoted healthful help group..
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International Medical Journal

Journal ID : IMJ-22-10-2019-8

Total View : 1555

Title : A Survey on Developing Viral Respiratory Diseases

Abstract : Rising infections have caused a colossal effect on humanity because of their sudden events at an irregular time and spot. Development of viral diseases happens when etiological infections cross their typical dens or fringes. These infections have stirred open mindfulness because of the promotion on different stages, particularly media. The explanation behind making such dangerous mindfulness is the looming high bleakness and mortality caused by these infections. Albeit the majority of them are non-antibody preventable, early clinical finding and palliative consideration with great disease control practices can counteract episodes and pandemics..
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Submission Deadline ( Vol 30 , Issue 04 )
20 Apr 2023

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Publish On ( Vol 30 , Issue 03 )
31 Mar 2023