International Medical Journal (ISSN:13412051)

Aim and Scope

Aim-

International Medical Journal ISSN: (13412051) is an international open-access journal publishes twelve times each year. The "International Medical Journal" is a peer-reviewed, monthly, online international research journal, which publishes original articles, research articles, review articles with top-level work from all areas of Medical Science Research and their application including Aetiology, bioengineering, biomedicine, cardiology, chiropody, ENT etc. Researchers in all Medical Science and Pharmacy fields are encouraged to contribute articles based on recent research. Journal publishes research articles and reviews within the whole field of Medical Science and Pharmacy Research, and it will continue to provide information on the latest trends and developments in this ever-expanding subject. International Medical Journal journal covers almost all disciplines of Medical Science and Pharmacy. Researchers and students of M.B.B.S, M.D., D.T.C.D., GYNE., M.S., M.Pharma, And PhD are requested to send their original research articles to International Medical Journal.

Scope-

International Medical Journal ISSN: (13412051) is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:

Anatomy Physiology Biochemistry Pharmacology
Pathology Forensic medicine Microbiology Community Medicine
Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology
Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases
Anaesthesia Cancer research Neurosurgery Orthopedics

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Latest Journals
International Medical Journal
Journal ID : IMJ-09-02-2020-219
Total View : 152

Abstract : Lupus nephritis (LN) is diagnosed by presence of proteinuria (0.5g per day or a dipstick score of > 3+) or red cell casts on microscopic urine analysis. Assessing histological severity and chronic lesions in LN is by renal biopsy. However, it is invasive and repeated biopsies are needed in monitoring treatment of LN. Therefore, new biomarkers for early diagnosis of lupus renal disease have to be searched. To evaluate urinary platelet factor4 (PF4) and vascular cell adhesion molecule-1(VCAM-1) as early markers of lupus nephritis. 120 patients with systemic lupus erythematosus (SLE) were involved and classified into 3 main groups; group I included 40 patients with inactive SLE, group II included 40 patients with active SLE without lupus nephritis and group III included 40 patients with active SLE with lupus nephritis. All patients were submitted to; urine analysis, complete blood count, fasting blood glucose, serum creatinine, liver function tests, serum complement 3, antinuclear antibody, anti-double stranded DNA level and urinary PF4 and VCAM-1 levels assays. Urinary PF4 and VCAM-1 levels were significantly higher in lupus nephritis group than in the other two groups. The cutoff value of PF4 in prediction of active lupus with nephritis is ≥7.93pg/ng with sensitivity 100% and specificity 90.5% and that of VCAM-1 is ≥783pg/ng with sensitivity 100% and specificity 93.8%. Urinary platelet factor 4 and vascular cell adhesion molecule-1 can serve as early markers for identifying LN.
Full article
International Medical Journal
Journal ID : IMJ-09-02-2020-218
Total View : 132

Abstract : Ischemic cardiomyopathy is the most frequent etiology of heart failure with reduced ejection fraction (HFrEF) and a result of ventricular structural, functional, and electrical remodelling. T peak to end (Tpe) interval is an electrocardiographic parameter that represent repolarization heterogeneity and had prognostic value for ventricular arrhythmia. Patients with Ischemic cardiomyopathy face a significant burden of arrhythmias. Mechanical dispersion is a functional remodelling parameter that can be measured by time to peak longitudinal strain using speckle tracking echocardiography. This study aims to assess the relationship between Tpe interval with time to peak longitudinal strain in ischemic cardiomyopathy patients. This study was conducted with observational analytical cross-sectional design. Ischemic cardiomyopathy subjects were included at Dr. Hasan Sadikin General Hospital, Bandung, from August to October 2019. Tpe interval was measured manually with tangential method. Time to peak longitudinal strain was measured using speckle tracking echocardiography. The correlation between Tpe interval and time to peak longitudinal strain was analyzed using Pearson correlation. A total of 30 subjects were included in this study. The average age was 58 ± 8 years old and the average left ventricular ejection fraction was 27 ± 5.5%. The average of Tpe interval was 83.4 + 7.62 ms and the average of time to peak longitudinal strain was 93.13 ± 34.51 ms. The Pearson correlation test showed a significant weak positive correlation (r=-0.386, 95% CI (0.029 – 0.743, p 0.018) between Tpe interval and time to peak longitudinal strain in ischemic cardiomyopathy patients. There was a significant weak positive correlation between Tpe interval and time to peak longitudinal strain in ischemic cardiomyopathy patients.
Full article
International Medical Journal
Journal ID : IMJ-08-02-2020-217
Total View : 149

Abstract : The aim of this study is to identify the genetic convergence between many strains of Pseudomonas aeruginosa that isolated from two different environments clinical samples and water samples. A total of 13 strains of Pseudomonas aeruginosa were collected, six isolates from clinical samples were obtained from patients attending in Al- Ramadi Hospital and seven samples of water from Faculty of Dentistry clinics /University of Anbar. Genotyping was done by employing the ERIC fingerprinting assay. The biofilm formation was tested by using Quantitative biofilm assay. The results of our study found genetic relatedness between the strains according to the molecular analysis of DNA using ERIC-PCR, revealed genetically identical among clinical strains and dental unites waterline strains. The 13 strains were divided in to three classes (I, II and III) according to molecular analysis of DNA results. The class I of P. aeruginosa include (P1, P2, P3, P4, P5, P9, P10 and P11 strains) that isolated from waterline dental unite and clinical samples. The class II of P. aeruginosa include (P8, P12 and P13) were isolated from clinical samples. The class III (P6 and P7) were grouped in the same cluster, these samples were obtained from water samples. Our study found that all isolates were producing biofilm and there are no significant differences between the isolates in forming biofilm (p 0.05). According to the statistic results the study found that class I have the highest ability to produce biofilm.
Full article
International Medical Journal
Journal ID : IMJ-07-02-2020-216
Total View : 133

Abstract : Salvia Officinalis (sage) is a plant which has been used since ancient times for its culinary and medicinal effects and the uses of antimicrobial agent to control plaque and oral disease has been advocated for a number of years. Different compounds have been delivered through mouth rinses or tooth pastes or by topical application. The purpose of this research is to find out and to compare between the anticariogenic properties of aqueous and alcoholic sage extract on the growth of causative cariogenic bacteria (salivary Lactobacilli). In the present study lactobacilli were isolated from saliva of twenty-five dental students (age range between 20-21 years). These bacteria were isolated, purified and diagnosed according to morphological characteristic, biochemical tests and Vitek 2 system. Lactobacillus casei, Lactobacillus plantarum, Lactobacillus salivarius, and Lactobacillus acidophilus were isolated from stimulated saliva of students under study. Agar diffusion technique showed that sage extracts (aqueous and alcoholic) were inhibited the growth of lactobacilli, and the diameter of inhibition zone increased as the concentration of sage extract increased, but the effect of aqueous extract was less than the effect of alcoholic extract. The minimum bactericidal concentrations of aqueous and alcoholic sage extract were 50%, 20% respectively. Alcoholic sage extract inhibits salivary lactobacilli higher than aqueous extract.
Full article
International Medical Journal
Journal ID : IMJ-06-02-2020-215
Total View : 262

Abstract : Stable coronary heart disease is the highest cause of death. This situation involves neutrophils and lymphocytes described by the neutrophil lymphocyte ratio (NLR) in inflammation. Inflammation makes an increase in acute phase protein C-reactive protein (CRP) and serum amyloid A (SAA), both of which also play a role in coronary artery stenosis. The degree of stenosis is measured by Gensini scores through invasive angiography. The relationship between the three hematological parameters and the degree of coronary artery stenosis needs a further investigation. A cross sectional study involving 35 stable coronary heart patients was calculated according to the formula of the sample size with inclusion and exclusion criteria. Examination of NLR was done by comparing absolute neutrophil counts, moreover absolute lymphocytes was examined by using a hematology analyzer. CRP levels were examined by the hs-CRP method and SAA levels were examined by using the ELISA principle. The Gensini score was used to assess coronary artery stenosis. The Spearman relationship test was used to analyze between variables. p <0.05 was considered significant. There is a significant positive relationship between NLR and SAA but no correlation between CRP and NLR and SAA. There is a significant positive relationship between NLR and SAA with Gensini scores. There is no relationship between CRP and Gensini score. NLR is a simple parameter and SAA is a biomolecular parameter, both of which increase with increasing weight coronary artery stenosis, in stable CHD patients, it can be used for evaluation of stable CHD patients.
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