International Medical Journal (ISSN:13412051)

Aim and Scope

Aim-

International Medical Journal ISSN: (13412051) is an international open-access journal publishes twelve times each year. The "International Medical Journal" is a peer-reviewed, monthly, online international research journal, which publishes original articles, research articles, review articles with top-level work from all areas of Medical Science Research and their application including Aetiology, bioengineering, biomedicine, cardiology, chiropody, ENT etc. Researchers in all Medical Science and Pharmacy fields are encouraged to contribute articles based on recent research. Journal publishes research articles and reviews within the whole field of Medical Science and Pharmacy Research, and it will continue to provide information on the latest trends and developments in this ever-expanding subject. International Medical Journal journal covers almost all disciplines of Medical Science and Pharmacy. Researchers and students of M.B.B.S, M.D., D.T.C.D., GYNE., M.S., M.Pharma, And PhD are requested to send their original research articles to International Medical Journal.

Scope-

International Medical Journal ISSN: (13412051) is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:

Anatomy Physiology Biochemistry Pharmacology
Pathology Forensic medicine Microbiology Community Medicine
Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology
Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases
Anaesthesia Cancer research Neurosurgery Orthopedics

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Latest Journals
International Medical Journal
Journal ID : IMJ-08-01-2020-130
Total View : 487

Title : Relationship between TOP2A mRNA Expression with Neoadjuvant Chemotherapeutic Response in Breast Cancer
by Prihantono, Mochammad Hatta, Andi Asadul Islam, I Made Christian Binekada, Daniel Sampepajung,
Abstract : Anthracycline is commonly used in neoadjuvant chemotherapy for breast cancer, although not all patients benefit from the therapy. Studies suggest that expression of TOP2A associated with Anthracycline sensitivity. Purpose: To know the relationship between the profile of baseline TOP2A mRNA expression and chemotherapy response in locally advanced breast cancer. An observational study, thirty breast cancer tissue samples pre-chemotherapy treated using cyclophosphamide-doxorubicin-5fluorouracyl regiment. Detection of TOP2A mRNA expression using qRT-PCR techniques. Clinical response to neoadjuvant chemotherapy based on RECIST criteria. The mean value of TOP2A mRNA expression in breast cancer patient’s prechemotherapy was 9.753±2.755, range 4.470–13.810. The mean value of TOP2A mRNA expression in breast cancer patients which responsive to chemotherapy was 10.601±2.208. The mean value of TOP2A mRNA expression in breast cancer patients, which nonresponsive to chemotherapy, was 6.969±2.648. Mean difference was 3.632, significant with p-value =0.001(p<0.05). There is a positive correlation between TOP2A mRNA expression with the clinical response with a value of r =0.475; this correlation was significant with p-value=0.004 (p<0.05). This study found a correlation between the profile of baseline TOP2A mRNA expression with clinical response to neoadjuvant chemotherapy in breast cancer.
Full article
International Medical Journal
Journal ID : IMJ-08-01-2020-128
Total View : 426

Title : Socioeconomic Disparities of Facility-Based Childbirth in Indonesia
by Agung Dwi Laksono, Astridya Paramita, Ratna Dwi Wulandari,
Abstract : In Indonesia, only 74% of women give birth in health care facilities. This study was conducted to analyze the socioeconomic disparities of facilities-based childbirth in Indonesia. The analysis in this study uses raw data from the 2017 Indonesia Demographic and Health Survey (IDHS). With stratification and multistage random sampling, 17,769 women aged 15-49 years with live births in the last 5 years were sampled. Data were analyzed using a Binary Logistic Regression test. Poorer women were 1.898 times more likely to use healthcare facilities for delivery than poorest women. Middle women were 2.669 times more likely to use healthcare facilities for delivery than poorest women. Richer women have 3.163 times more opportunities to use healthcare facilities for delivery than poorest women. The richest women were 6.566 times more likely to use healthcare facilities for delivery than the poorest women. Women who live in urban areas were 2.412 times more likely to use healthcare facilities for delivery than those who live in rural areas. Age, parity, level of education, ownership of health insurance, knowledge of the danger signs of pregnancy, and antenatal care, in maternity women the past five years significantly contribute to the utilization of healthcare facilities for delivery. There was a significant disparity between socioeconomic in utilizing healthcare facilities for delivery in Indonesia. Women with better socioeconomic status have better possibilities for utilizing healthcare facilities for delivery.
Full article
International Medical Journal
Journal ID : IMJ-06-01-2020-126
Total View : 463

Title : A comparative CBCT Iraqi study to assess sella turcica form and size in subjects with cleft lip or palate
by Nihad A. Hassan, Sanaa J. M. Alqassab, Maisaa K. M. Ali, Amal Raouf Mohammed, Amal Kadhem Chaloob,
Abstract : The focus of this study was to assess sella turcica size and shape utilizing advanced image; and to find if there is any significant difference in these variables of sella turcica as concerns to the gender, age, and groups. Data included 41 CBCT images divided into two groups: a patient group with cleft lip or palate (20 patients: 7 females and 13 males, aged between 16 and 26 years) and control group (21 subjects: 9 females and 12 males, aged between 17and25 years). Linear measurements such as length, depth, and diameter of sella turcica were investigated and its shape was described in each group. Information was analyzed by using the SPSS version 21 to compare between groups and find any statistical significance. The means of all variables appeared bigger in cleft (length: 9.65; depth: 7.94; diameter: 11.61) than normal (length: 8.6; depth: 7.79; diameter: 11.48) groups. Furthermore, each age and length observed statically significant differences between two groups (T-test:3.280, p-value:.002; T-test: 3.056, p-value:0.002) respectively. The anatomical study of sella turcica including form and dimension in normally and its difference using CBCT could be valuable for the dentist to analyze differences associated with cleft conditions and realized the reason of some signs for good diagnosis and prognosis.
Full article
International Medical Journal
Journal ID : IMJ-06-01-2020-125
Total View : 584

Title : Factor V Deficiency in an Adolescent: A Case Report
by Danish Zia, Hiba Rauf, Uzair Yaqoob, Mir Tahir Hussain Talpur, Ibad Ali Khan Ghori, Lajpat Rai,
Abstract : Factor V is a major part of the coagulation system and maintains a balance in pro-coagulant and anticoagulant pathways. Any deficiency or mutation can lead to disequilibrium. Factor V deficiency presents with bleeding while Factor V Leiden leads to a hypercoagulable state. Factor V deficiency can be congenital or acquired. The clinical findings range from asymptomatic to life-threatening hemorrhage. Prothrombin time and Activated partial thromboplastin time are elevated. The management includes Fresh frozen plasma infusion. This is a case of a 14-years-old female presenting with menorrhagia and hemorrhagic ovarian cyst, diagnosed as congenital factor V deficiency after factor V assay. Initially, it was considered a platelet functional defect. As seen in the current report, it is observed that patients with factor V deficiency present early in life with mucocutaneous bleeding, so early diagnosis and prompt management plays an important role in order to avoid the severe symptoms in future.
Full article
International Medical Journal
Journal ID : IMJ-06-01-2020-124
Total View : 452

Title : An Alternative Method of Induction of Type II Diabetes Mellitus in Sprague Dawley Rat
by Holifa Saheera Asmara, Nasir Mohammad, Ahmad Zubaidi Abdul latif,
Abstract : The induction of the type II diabetes model in Sprague Dawley rat is commonly performed for further laboratory experimental purposes. The main characteristic of type II diabetes mellitus is insulin resistance, which highly associated with high-fat and high-sugar diets. Therefore, to develop this condition, the current study proposed an alternative procedure of induction, wherein includes a combination of a high-fat diet with multiple injections of streptozotocin and immediately, 5% glucose drinks were administered after the injection to enhance the hyperglycemic and insulin resistance state in the rat. This protocol successfully developed the hyperglycemic state. Poor glucose clearance indicated insulin resistance in the rat.  In conclusion, this protocol provides an alternative procedure in inducing insulin resistance and a hyperglycemic state of type II diabetes mellitus in Sprague Dawley rat.
Full article
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