: PTA has multifactorial etiology involving transplant failure, infections, co-morbidity, inflammation, ACE inhibitors/ ARBs, and immunosuppressive treatment. Anemia complicates chronic kidney disease and has been associated with increased mortality in dialysis patients. Anemia is corrected after renal transplantation, yet PTA is noted in 20% to 40% cases. This study was carried out to determine the association of anemia factors in kidney transplant recipients with and without post-transplantation anemia. After informed consent, demographic information of all the study subjects (including name, age, and gender) was recorded. The patient’s hemoglobin level was checked and they were labeled as anemic or non-anemic. In all anemic and non-anemic patients, study parameters were applied to rule out the cause of anemia. All the information was collected on a specially designed proforma. The following study parameters were measured using the standard lab procedures and manufacturer’s instructions. Using logistic regression, we found that in these patients serum B12 deficiency, low serum folate, and low serum iron were significant factors of anemia with a significant Odds ratio (i.e. OR>1) i.e. 5.913, 60.945 and 51.825 respectively. Medical complications are common after renal transplant especially in the early postoperative period. The only way forward is early recognition and aggressive treatment, as delays can cost losses in the form of kidney function, life, and higher health care cost.