International Medical Journal

Journal ID : IMJ-04-01-2022-1149

Total View : 435

Title : Comparison vacuum -assisted closure system and conventional dressing on wound healing in patient with leg ulcer

Abstract :

One of the most common causes for admission in surgical ward is non healing ulcer. In which diabetes is the most common etiology. In most of the cases, hospital stay of many weeks is required for management of the above. In many cases they ultimately go for amputation. Acute and chronic wounds affect at least 1% of the population. In all sense patients turns to be a burden for society and family. Vacuum assisted closure is a universally accepted method for dressing. It has proved its efficacy for wound dressing. Faster wound healing, shorter hospital stay.Still in our hospital, majority of dressings are conventional our aim is to show the advantage of V.A.C over conventional dressing in our hospital on wound healing. Total 50 patients were enrolled They are divided in to two groups one for conventional dressing group Department of general surgery , Dr D YPatil medical college , hospital and research center , Pimpri, Pune, Dr D Y Patil vidyapeeth, Pune and the other for VAC.Out of 50 patients 25 patients got the VAC dressing done and 25 conventional dressing. Significant reduction in ulcer size was noted in patients with VAC dressing as compared to conventional dressing.VAC therapy is a contemporary technique for the treatment of wounds. Its introduction has transformed the path of wound care. Based on the findings from the present study and other studies available, VAC assisted wound care results in improved wound healing ( reduction in wound size and formation of healthy granulation) and at a faster rate.

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International Medical Journal

Journal ID : IMJ-04-01-2022-1148

Total View : 486

Title : The study on prevalence of eosinopenia and lymphopenia in covid-19 patients and its importance in predicting the disease severity – a retrospective observational study

Abstract : Early detection of COVID 19 is necessary as it has caused increased global mortality along with a variety of manifestations and rapid progression. There are many markers of COVID 19 viral pneumonia but the exist a few predictors of its severity. To observe the prevalence and importance of Eosinopenia and Lymphopenia in predicting severity of COVID-19 cases. The current study involved 81 cases of COVID 19 viral pneumonia of which 40 were classified as mild while 41 were severe requiring ICU care. The relatability between the lymphocyte and eosinophil count of the admitted patients, for severity and outcome of the disease was analysed using statistical analysis software. Among the study participants, 41 were severe cases which required ICU care and 40 were mild cases which required ward care. Out of the 41 severe cases, all 41 patients (100%) were found to have eosinopenia while 28 patients (68.3%) were found to have lymphopenia. Additionally, among the severe cases, 28 patients (68.3%) were found to have both eosinopenia and lymphopenia. A significant association was also found between lymphopenia and Acute Kidney Injury. A significant association was also observed between the presence of eosinopenia, lymphopenia and both simultaneously, and mechanical ventilation. In this study it was found that eosinopenia and lymphopenia can be considered as a marker of severity of COVID 19, thus if admission sample of Complete blood count shows eosinopenia or lymphopenia, such patients must be given vigorous treatment as probability of worsening of clinical condition is higher..
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International Medical Journal

Journal ID : IMJ-04-01-2022-1146

Total View : 375

Title : Effect of the solvent concentration and pH on polyphenol, chlorophyll content, and antioxidant activity of Hydrocotyle asiatica grown in Southern Center, Vietnam

Abstract : The impact of extraction condition of antioxidant polyphenol and chlorophyll from species Hydrocotyle asiatica grown in Vietnam was presented in the current study. The extraction condition was studied composed of solvent concentrations (60 to 100 with jump step (δ) of 5) and solvent pH (2 to 10 with δ of 1). Besides the content of polyphenol and chlorophyll, the target function of antioxidant activity was also evaluated based on total antioxidant activity and reducing power activity. The results showed that polyphenol and chlorophyll content and antioxidant activity from Hydrocotyle asiatica were affected by the solvent concentration and solvent pH significantly (p<0.05). The content of polyphenol (3.958±0.028 mg gallic acid equivalent/g DW) and chlorophyll (2.412±0.057 mg/g DW), and the antioxidant activity composed of total antioxidant activity (2.077±0.022 mg ascorbic acid/g DW) and reducing power activity (11.366±0.53 mg FeSO4 equivalent/g DW), was the highest at 95% ethanol and solvent (pH 5), compared to other conditions. Polyphenol, chlorophyll content, and antioxidant activity were changed according to the model of level 2 under the impact of solvent concentration and solvent pH. The results were valuable in the antioxidant polyphenol and chlorophyll extraction for applicating functional food and pharmaceuticals..
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International Medical Journal

Journal ID : IMJ-04-01-2022-1143

Total View : 472

Title : Demographic and Clinical Profile of Right Iliac Fossa Mass: A Prospective Study

Abstract : Mass in the right iliac fossa has a very high incidence rate among the cases of lump in abdomen. It’s a diagnostic and therapeutic challenge to surgeons due to the detailed anatomy of the region and varied etiology. To study the demographic profile of right iliac fossa mass. In this prospective comparative study, total 50 cases were studied for duration of 2 years. Detailed demographic data was obtained after confirming the diagnosis. Necessary management was done. Comparison of all the data with various demographic parameters was done to reach conclusion. Maximum cases were from age group of 31-40 yrs with mean age was 40.76 years and male predominance (58%). Appendicular lump (28%) was most common diagnosis among study subjects followed by ileocaecal tuberculosis (14%). Farmers and labourers were more prone to develop mass in right iliac fossa. Mass in right iliac fossa is commonly seen in males of age group 31 to 40 years with low socioeconomic status. Appendicular mass is most common pathology in RIF region although ileocaecal tuberculosis also have good incidence rate. Due to its varied presentation, high index of suspicion is absolutely necessary for diagnosis and management of right iliac fossa mass..
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International Medical Journal

Journal ID : IMJ-04-01-2022-1142

Total View : 366

Title : Toluidine Blue as Diagnostic Tool in the Detection of Premalignant Oral Lesions

Abstract : Oral cancer is the most common type of cancer affecting large population in India. Tobacco consumption including smoking and smokeless tobacco are some of the risk aspects for the incidence of oral cancer. Detection of premalignant oral lesions reduces the overall mortality from the disease and from the treatment procedures of oral cancer. Toluidine Blue is an acidophilic dye which has affinity for DNA and RNA present excess in dysplastic cells. In our study we have used Toluidine Blue as diagnostic test to detect premalignant oral lesions. Prospective study done in Dr. D. Y. Patil Medical College, Hospital &Research Centre, Pimpri, Pune, Under Department of General Surgery from July 2019 to August 2021. Patients presenting with oral lesions and who has risk factors for developing oral cancer were stained with an aqueous solution of 1% Toluidine blue, stained lesions were subjected to biopsy and histology. Sensitivity, Specificity and diagnostic accuracy of Toluidine Blue in detecting oral premalignant lesions among our study sample was 96.15%, 77.78%, 91% respectively. Toluidine Blue stain aids in diagnosing Premalignant Oral Lesions with good sensitivity and specificity. It is also simple, low cost and easily available..
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International Medical Journal

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Submission Deadline ( Vol 30 , Issue 09 )
20 Sep 2023

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Publish On ( Vol 30 , Issue 07 )
31 Jul 2023