International Medical Journal (ISSN:13412051)

Aim and Scope

Aim-

International Medical Journal ISSN: (13412051) is an international open-access journal publishes twelve times each year. The "International Medical Journal" is a peer-reviewed, monthly, online international research journal, which publishes original articles, research articles, review articles with top-level work from all areas of Medical Science Research and their application including Aetiology, bioengineering, biomedicine, cardiology, chiropody, ENT etc. Researchers in all Medical Science and Pharmacy fields are encouraged to contribute articles based on recent research. Journal publishes research articles and reviews within the whole field of Medical Science and Pharmacy Research, and it will continue to provide information on the latest trends and developments in this ever-expanding subject. International Medical Journal journal covers almost all disciplines of Medical Science and Pharmacy. Researchers and students of M.B.B.S, M.D., D.T.C.D., GYNE., M.S., M.Pharma, And PhD are requested to send their original research articles to International Medical Journal. Azerbaijan Medical Journal Gongcheng Kexue Yu Jishu/Advanced Engineering Science Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery Interventional Pulmonology

Scope-

International Medical Journal ISSN: (13412051) is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:

Anatomy Physiology Biochemistry Pharmacology
Pathology Forensic medicine Microbiology Community Medicine
Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology
Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases
Anaesthesia Cancer research Neurosurgery Orthopedics

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Latest Journals
International Medical Journal
Journal ID : IMJ-28-04-2022-1394
Total View : 426

Abstract : Regional anaesthesia has lot of advantages compared to general anaesthesia for urological surgeries. Bupivacaine is been widely used for spinal anaesthesia across the globe, in spite of its dense motor blockade and cardiac toxicity. In 2009 Ropivacaine, which is a S-enantiomer of bupivacaine, an aminoamide local anaesthetic was introduced in India, though it was being used in other parts of the world since early 1990s. The advantage of Ropivacaine is that it produces less motor blockade which makes it favourable for ambulatory surgeries and urological surgeries which does not require dense motor blockade. The aim of this study was to determine the safety profile and efficacy of two different concentrations of intrathecal isobaric Ropivacaine (0.5 % and 0.75 %) in patients undergoing elective urological surgery.60 Patients who were posted for urological surgery were selected and were divided into two groups (30 in each group) A and B. Group A was given0.5% Isobaric Ropivacaine and Group B wasgiven0.75% Isobaric Ropivacaine. SPSS 24 was used for statistical analysis. The time of onset of sensory block at T10 and time for maximum sensory block was significantly lower (p<0.05) in Group B on comparison with Group A. The time for two segment sensory regression and the total duration of sensory block was significantly lower (p<0.05) in Group A on comparison with Group B. The time of onset of motor block and time for maximum motor block was significantly lower (p<0.05) in Group B on comparison with Group A while the total duration of motor block was significantly higher (p<0.05) in Group B.Group A (0.5% isobaric Ropivacaine) provided adequate anaesthetic conditions for urological surgeries inspite of its delayed sensory onset when compared to Group B (0.75% isobaric Ropivacaine)..
Full article
International Medical Journal
Journal ID : IMJ-27-04-2022-1393
Total View : 365

Abstract : Chronic alcohol exposure has altered the prognosis and diagnosis of alcoholic liver disease (ALD) by non-coding RNAs (ncRNAs), gene expression and regulating the protein in the hepatic disease process. Many studies have shown that ncRNAs are involved in various biological processes and the progression of diseases. Long non-coding RNAs (lncRNAs), micro-RNAs (miRNAs), and circular RNAs (circRNAs) are major groups in ncRNAs that attract attention. Recently, RNA sequencing technologies have improved with advanced knowledge of molecular regulation pathways of lncRNAs and miRNAs. The aberrant role of lncRNAs followed by hepatic disease progression and significant regulatory role in biological processes, like cellular growth, cell cycle, proliferation, apoptosis, transcriptional factor regulation, etc. Hepatic fibrosis is a flexible wound healing process followed by accumulation of extracellular matrix (ECM) formation. Similarly, up and downregulation of lncRNAs affect cellular integrity and ECM accumulation in the liver disease progression. In hepatic disease progression, most lncRNAs regulate the cellular hemostasis process and therapeutic targets as potential biomarkers in clinical practice. It is of great significance to acquire a full knowledge of the biological processes and regulation of molecular mechanisms underlying hepatic injuries to find and target specific and sensitive molecules for hepatic regeneration. Therefore, lncRNAs have attracted considerable interest in the hepatic regeneration of following alcoholic abuse. In this review, we focus on the predictive role of lncRNAs regulatory factors that induced hepatic growth and regeneration..
Full article
International Medical Journal
Journal ID : IMJ-27-04-2022-1392
Total View : 439

Abstract : Diabetic retinopathy is a significant cause of blindness in Saudi Arabia and worldwide. One in five people in Saudi Arabia is suffering from diabetes mellitus. Obstructive sleep apnea and diabetes when co-exist aggravate each other with deleterious consequences. We aimed to assess the relationship between obstructive sleep apnea and diabetic retinopathy in Tabuk, Saudi Arabia. This is a sectional study conducted at the Diabetes Center in King Fahd Specialist Hospital, Tabuk City, Saudi Arabia during the period from August 2021 to February 2022. Two hundred and eight patients with type 2 diabetes were included. A structured questionnaire was used to collect socio-demographic and cardiovascular risk factors. Obstructive sleep apnea risk was assessed by the STOP-BANG questionnaire. The Statistical Package for Social Science was used for data analysis. There were 208 patients with type 2 diabetes, their age was 51.98±12.90 years; the body mass index was 32.28±9.38, the duration of diabetes was 10.97±10.70, the Stop-Bang score ranged from 1-7 (mean± SD, 4.37±1.61) and the HBa1C was 9.44±1.67. Obstructive sleep apnea was highly prevalent (84.6%) and diabetic retinopathy was evident in nearly half of the patients (48.1%). No significant statistical difference was evident between patients with and without retinopathy regarding obstructive sleep apnea risk (4.7±1.7 versus 3.9±1.4, 95% CI, -0.14-1.6, P-value, 0.093. Obstructive sleep apnea and diabetic retinopathy were highly prevalent. No significant statistical association was evident between obstructive sleep apnea risk and diabetic retinopathy. Further larger multi-center studies are needed..
Full article
International Medical Journal
Journal ID : IMJ-26-04-2022-1391
Total View : 461

Abstract : The current study assessed the effect of Photobiomodulation [PBM] in combination with either Calcium Hydroxide [Ca(OH)2] or Mineral Trioxide Aggregate [MTA] as dental pulp capping agents on dental pulp exposures of dogs’ teeth. Ninety six teeth in 6 healthy mature dogs were divided in random into two major study groups; group I where calcium hydroxide was used as a pulp capping and group II in which MTA was used. Each group was subsequently divided into two subgroups, group (A) with no PBM and group (B) with PBM. The subgroups were consequently divided according to the observation period following completion of pulp capping into 1week (1W), 8 weeks (8W), and 16 weeks (16W). The teeth were examined for histological inflammatory response as well as dentine bridge formation. With regards to inflammatory response at 1 week significantly less intense inflammation was observed in PBM Ca(OH)2 group and PBM MTA compared to the no PBM Ca(OH)2 group and no PBM MTA group for the same time period. As for dentin bridge formation PBM MTA groups showed thicker dentine bridge formation at 16 weeks than no PBM MTA group for the same time period. Under the conditions of this study, laser irradiation appeared to be a beneficial adjunct in dental pulp capping procedures in which MTA was the pulp capping material..
Full article
International Medical Journal
Journal ID : IMJ-26-04-2022-1390
Total View : 456

Abstract : This retrospective cohort study aims to estimate the prevalence rate of Hepatitis B infected patients at the District Rawalpindi and Islamabad, Pakistan. A total of 490 infected patients’ complete medical records were collected with the help of a standard prepared questionnaire containing demographic details, hepatic complaints, past and present illness, physical examination records and other diagnostic laboratory reports. All 490 collected medical records were analyzed using GraphPad Prism (Version 8.40). The Pearson chi-square test was used with confidence level = (95 %) and a statistically significant P-value <0.05 was considered. Of 490 medical records, 72 (14.69%) patients found positive for Hepatitis B infection, including male 39 (18.93%) and female 33 (11.61%). Patients were more prevalent 3 (25%) in the age of <10 years. The highest prevalence was reported in the month of November 9 (32.14%) followed by February 18 (24%). Similarly, the higher ratio of 20 (19.41%) of Hepatitis B was reported in 2020 as compared to the 2021 year 52 (13.43%). Moreover, the highest seropositivity of HBsAg has resulted via quantitative Real-Time PCR 29 (27.88%), followed by Enzyme-Linked Immunosorbent Assay 39 (5.66%), qualitative PCR were 03 (10%) and by Immune-chromatography test was only 1 (0.93%) specimen. The quantitative Real-Time PCR had higher sensitivity and seropositivity and was considered the best method for the diagnosis of Hepatitis B infection. It was concluded that individuals of these localities are highly burdened by hepatitis B viral infection which should devise proper preventive measures to reduce the risk of infection..
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