International Medical Journal (ISSN:13412051)

Aim and Scope

Aim-

International Medical Journal ISSN: (13412051) is an international open-access journal publishes twelve times each year. The "International Medical Journal" is a peer-reviewed, monthly, online international research journal, which publishes original articles, research articles, review articles with top-level work from all areas of Medical Science Research and their application including Aetiology, bioengineering, biomedicine, cardiology, chiropody, ENT etc. Researchers in all Medical Science and Pharmacy fields are encouraged to contribute articles based on recent research. Journal publishes research articles and reviews within the whole field of Medical Science and Pharmacy Research, and it will continue to provide information on the latest trends and developments in this ever-expanding subject. International Medical Journal journal covers almost all disciplines of Medical Science and Pharmacy. Researchers and students of M.B.B.S, M.D., D.T.C.D., GYNE., M.S., M.Pharma, And PhD are requested to send their original research articles to International Medical Journal.

Scope-

International Medical Journal ISSN: (13412051) is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:

Anatomy Physiology Biochemistry Pharmacology
Pathology Forensic medicine Microbiology Community Medicine
Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology
Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases
Anaesthesia Cancer research Neurosurgery Orthopedics

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Latest Journals
International Medical Journal
Journal ID : IMJ-03-01-2020-119
Total View : 498

Abstract : To find the causes of surgical cancellations in patients attending a preoperative assessment clinic and scheduled for surgery at our institution. This audit included all those patients who presented to the preoperative assessment clinic with their surgeries planned in the main operating rooms of our hospital. The duration of this audit was three months. Canceled cases were identified from the operating room lists and the reasons for cancellations were categorized into two factors. forty-seven (47) cancellations were identified; clinical problem (66%) and administration factors (34%). In clinical problems, the most common causes are upper respiratory tract infections (URTI) and listen for wheezes, cough, rales, or lower airway rhonchi preoperative examination, which was found on 9 (19%) and 8 (17%) patients. Meanwhile, the availability of NICU (neonatal intensive care unit) or PICU (pediatric intensive care unit) space is the main reason for surgical cancellation related to administration factors, amounting to 8 (17%) Patients (Table 3A and Table 3B). Most of the patient-related factors were found to be uncontrollable. Administration factors related to cancellations might be reduced with better communication between Anesthetic themselves and the surgeons.
Full article
International Medical Journal
Journal ID : IMJ-02-01-2020-117
Total View : 374

Abstract : Leptin is an ob (obesity) gene, a fat tissue determined hormone that assumes the main role in the guideline of muscle versus fat mass by regulating hunger and digestion while adjusting vitality admission and use. The objective of this study was to assess the conceivable relationship between serum leptin levels, lipid profile and Body Mass Index (BMI) between smokers and nonsmokers. One-hundred and eight subjects of 18 to 26 years males of ASU students were randomly chosen in this study. The subjects were grouped according to smoking criteria (53 smokers and 55 nonsmokers). After a complete assessment, statistical information was recorded and BMI. Fasting blood tests were attracted to quantify serum leptin, serum glucose, and triglycerides (TG), low-density lipoprotein (LDL), high-density lipoprotein (HDL), and Cholesterol levels. The significance of the measured values and their correlation and regression (p and r) with the smoking habit using SPSS package version 22 were calculated. Serum leptin levels and differences between smokers and nonsmokers were not significant. The mean values for smoker leptin were 10.52 ±9.79 ng/ml and 11.17±9.09 ng/ml for non-smokers. The leptin levels were highly significant at (p<0.001) with BMI and subject weight, the leptin level of subjects with BMI (30 to 34.9) was 23.61±2.05 ng/ml and 28.45±1.2 ng /ml in those of BMI >35. The levels of serum leptin for non-smokers and smokers are not significant regardless of being on the borderline of the upper value of 9.2, whereas, leptin levels expand with BMI in overweight and obese subjects compared to normal BMI (18.5-25).
Full article
International Medical Journal
Journal ID : IMJ-02-01-2020-116
Total View : 511

Abstract : Chronic obstructive pulmonary disease (COPD) is a non-infectious disease that has become a public health problem in Indonesia. We examine the relationship between smoking risk factors, lower respiratory tract infections, leukocyte count (eosinophil, neutrophil, and lymphocyte), and thoracic rays and varying degrees of stable COPD. This study is quantitative and uses a cross-sectional research design. Samples were taken from patients with stable COPD who were treated in Sukapura Jakarta Islamic hospital. The date of the study on November 30, 2017. There were 37 patients as samples study using a total sampling technique. The data used in this research are secondary data from the COPD patient medical records. The chi-square test was employed. This test is used to identify whether or not there is a significant relationship between independent variables and a dependent variable. Statistical tests were completed using SPSS 16.0. The most prevalent COPD risk factor associated with a moderate degree of COPD was being a smoker. The degree of COPD was obtained from leukocytosis results from 13 patients. The degree of severe COPD was obtained from the results of the chest x-ray of 1 patient. The most severe degree of COPD was obtained from the high neutrophil results of 2 patients. The majority of COPD patients included moderate COPD, including more severe smokers, those who had smoked for over 30 years, and trends including bronchitis, leukocytosis, low ESR, eosinopenia, neutropenia, and lymphocytopenia.
Full article
International Medical Journal
Journal ID : IMJ-02-01-2020-115
Total View : 275

Abstract : Benign Prostatic Hyperplasia (BPH) is the most frequent disease in elderly men, but the exact pathogenic mechanism of the disease is still largely unknown. The etiology of infection that induces inflammation plays an important role in the pathomechanisms of BPH. Propionibacterium acnes (P. acnes) is a microorganism that is often found in prostate tissues. We investigate the frequency of P. acnes and its relationship with prostate inflammation in patients with BPH. Cross-sectional research was conducted in several hospitals in Indonesia. A total of 50 BPH patients undergoes the procedure of transurethral resection of the prostate, DNA examination of P.acnes with Multiplex Touchdown PCR, and the examination of IL-6 and IL-8 by ELISA. Of the 50 patients underwent the examination of the PCR, 14 (28%) were positive P. acnes and 36 (72%) were negative P. acnes. Histopathological examination results revealed that all patients with BPH and prostatitis (100%) show the increasing level of IL-6 with an average of 490.5 ± 242.2 pg/ml while the level of IL-8 had an average of 118.3 ± 50.4 pg/ml. With statistical tests, it was obtained that there was a significant association between P. acnes and the increased level of IL-6 and IL-8. The present study provides further evidence for the role of P.acnes in prostate inflammation. P. acnes can be a contributing agent by triggering cell proliferation.
Full article
International Medical Journal
Journal ID : IMJ-01-01-2020-114
Total View : 494

Abstract : Acute myocardial infarction (AMI) is a critical condition that requires urgent intervention. The goals of treatment are usually to restore the patency of the affected coronary artery, and myocardial reperfusion within a relatively short time period. Many thrombolytic drugs can meet these criteria. However, successful thrombolysis cannot be easily confirmed or predicted. To evaluate the predictive values of QT interval and QRS duration dispersions for successful thrombolysis in patients with acute ST-elevation myocardial infarction. This is an observational prospective study which included a total of 90 adult patients with acute ST-elevation myocardial infarction (STEMI) that underwent therapeutic thrombolysis. Electrocardiographic (ECG) traces were carried out at patient’s admission, immediately before and 90 minutes post infusion of thrombolytic drug. Traces were analyzed by a single observer, with no previous knowledge on the status of the patient. Sixty-six patients were treated with alteplase, while tenectaplase was used to treat the other 24 patients. Response to thrombolytic drug was defined as ≥50% decrease of maximum ST elevation 90 minutes after the initiation of thrombolytic drug. From each ECG trace, the corrected QT dispersion (QTcd) and QRS dispersion (QRSd) were calculated. Receiver operating characteristic (ROC) curves were used to assess the QRSd and QTcd as predictors for successful thrombolysis as indicated by regression of maximum ST elevation. Values of both QRSd and QTcd were comparable between alteplase and tenectaplase-treated patients before and after treatment with no significant differences. In both groups, there were significant reductions in both QTcd and QRSd 90 minutes after thrombolytic treatment. In alteplase-treated patients, the sensitivity and specificity of QRSd for prediction of successful thrombolysis at cut off value of 22 ms were 68% and 67% respectively, and for QTcd at cut off value of 72 ms were 79% and 87% respectively. In, tenectaplase-treated patients, the sensitivity and specificity of QRSd at cut off value of 12 ms were 84% and 82% respectively, and for QTcd at cut off value of 49 ms were 80% and 74% respectively. Thrombolytic therapy causes a marked reduction in QRS and QTc dispersion. QRS and QTc dispersion have good sensitivity and specificity in predicting successful thrombolysis, which was more prominent in tenectaplase than in alteplase-treated patients with STMI. Using the combination of QRSd and QTcd can increase the predictive values of ECG parameters for successful thrombolysis.
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