International Medical Journal (ISSN:13412051)

Aim and Scope

Aim-

International Medical Journal ISSN: (13412051) is an international open-access journal publishes twelve times each year. The "International Medical Journal" is a peer-reviewed, monthly, online international research journal, which publishes original articles, research articles, review articles with top-level work from all areas of Medical Science Research and their application including Aetiology, bioengineering, biomedicine, cardiology, chiropody, ENT etc. Researchers in all Medical Science and Pharmacy fields are encouraged to contribute articles based on recent research. Journal publishes research articles and reviews within the whole field of Medical Science and Pharmacy Research, and it will continue to provide information on the latest trends and developments in this ever-expanding subject. International Medical Journal journal covers almost all disciplines of Medical Science and Pharmacy. Researchers and students of M.B.B.S, M.D., D.T.C.D., GYNE., M.S., M.Pharma, And PhD are requested to send their original research articles to International Medical Journal. Azerbaijan Medical Journal

Scope-

International Medical Journal ISSN: (13412051) is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:

Anatomy Physiology Biochemistry Pharmacology
Pathology Forensic medicine Microbiology Community Medicine
Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology
Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases
Anaesthesia Cancer research Neurosurgery Orthopedics

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Latest Journals
International Medical Journal
Journal ID : IMJ-05-02-2020-207
Total View : 172

Abstract : Antioxidant phlorotannins are the high-value biopolymer in brown algae. The paper focused on the impact of cobalt-60 irradiation on phlorotannin content and antioxidant activities of brown algae Sargassum serratum commonly found growing in the tropical marine area of South Center, Vietnam. The irradiation dose (0, 5, 10, 15, 20, 25 kGy) and techniques (dry-and wet-irradiation) was studied. The results showed the various cobalt-60 irradiation of doses and techniques affected phlorotannin content and antioxidant activities (p<0.05) that changed according to the non-linear equation and close correlation (R2 > 0.9). Phlorotannin content was the highest at an irradiation dose of 5 kGy. Total antioxidant, reducing power and DPPH free radical scavenging activity of the species got the highest value at an irradiation dose of 25 kGy, corresponded to 0.827 ± 0.019 mg ascorbic acid equivalent/g DW, 0.273 ± 0.006 mg FeSO4 equivalent/g DW and 70.27 ± 1.85%, respectively. The impact of wet irradiation techniques on antioxidant phlorotannins were stronger, compared to dry irradiation techniques.
Full article
International Medical Journal
Journal ID : IMJ-05-02-2020-205
Total View : 139

Abstract : In 2013, Asia-Pacific leaders formed Malaria Alliance (APLMA) and declared goal of regional malaria elimination by 2030. Plasmodium vivax is the predominant malaria species in Asia-Pacific, and accounts for >80% of the global burden. Strategies aimed for P. falciparum may not give impact for the elimination of P. vivax as it is not targeting the parasite liver stage. Primaquine remains the only drug that has the ability of killing parasite in the liver. World Health Organization recommended that primaquine should be given over 14 days, thus an observational study in Papua, Indonesia, found that the compliance to unsupervised PQ was estimated to be only 12%. Single dose of tafenaquine as radical treatment sounds promising, however it also poses Glucose-6-phosphate deficiency individuals to the risk of hemolysis, and determine the G6PD status prior to prescribing the drug is crucial. In this paper, we will review several challenges in achieving P. vivax elimination, especially in the Asia-Pacific.
Full article
International Medical Journal
Journal ID : IMJ-05-02-2020-204
Total View : 259

Abstract : The case was found first as chronic myelogenous leukemia (CML), based on clinical sign and peripheral blood morphology, but later showed signs of acute lymphoblastic leukemia (ALL). A 35-years-old patient came to the hospital emergency room for the first time, complained of abdomen enlargement since a few months ago. Physical examination showed conjunctival anemia and splenomegaly equal with Schuffner 6, but no lymphadenopathy was found. Laboratory test showed normocytic normochromic anemia, severe leukocytosis, thrombocytopenia, and increased of reticulocytes. Bone marrow puncture (BMP) results were hypercellular, increased granulopoeisis activity, decreased erythropoeisis and megakaryopoeisis, with lymphoblasts were 24% and myeloblasts were 1%. Sokal score calculation was obtained 5.83, classified as high risk of CML. A flowcytometry test found positive of  CD34, CD19, and CD 79a and lead diagnosis to B cell acute lymphoblastic leukemia (B-ALL). The case showed the condition of CML transformed into ALL which obscured the initial diagnosis of CML.
Full article
International Medical Journal
Journal ID : IMJ-04-02-2020-203
Total View : 156

Abstract : The purpose of the study was to investigate the immune response in patients with recurrent pyelonephritis depending on the presence of hyperoxaluria.The observational cross-sectional study involved 64 women with recurrent pyelonephritis. The patients’ immune response was evaluated by determination of serum concentrations of interleukins (IL) -4, -17, -18, -23, tumor necrosis factor-alpha (TNF-α) and monocyte chemoattractant protein 1 (MCP-1). Depending on the presence of hyperoxaluria (urinary oxalate excretion was more than 0.45 mmol per day), the patients were allocated into 2 groups: the women with hyperoxaluria were included to group I (n = 35) and the patients with normal levels of oxalate excretion were included to group II (n = 29). The control group consisted of 25 practically healthy donors.The mean age in the patient population was 31.6 ± 7.7. The average number of pyelonephritis recurrence was 6.4 ± 1.9 per year. We identified a moderate direct correlation between the levels of the urinary oxalate excretion and the number of pyelonephritis recurrences per year (r = 0.71, p < 0.0001) and the inverse strong correlation between oxaluria and GFR level (r = 0.75, p < 0.0001). The patients with hyperoxaluria had increased synthesis of the blood concentration of TNF-α, MCP-1, IL -4, -17 and 23. Our results have provided preliminary evidence that hyperoxaluria is associated with increased serum levels of IL-4, -17, -23, MCP-1 and TNF-α. The larger-scale studies are needed for further confirmation of our findings.
Full article
International Medical Journal
Journal ID : IMJ-04-02-2020-202
Total View : 166

Abstract : Obesity is an excess of body fat and characterized by adipose tissue dysfunction causes an increase in proinflammatory adipocytokines, including C-Reactive Protein (CRP). Studies have shown the increasing of CRP levels in obese patients. C-reactive protein can cause left ventricular remodeling by myocyte biological remodeling, myocyte apoptosis and degradation of extracellular matrix which cause changes in myocardial mechanics and changes in left ventricular systolic function. This study aims to investigate the hs-CRP as a marker of subclinical left ventricle (LV) systolic dysfunction in young adults with obesity. This study was conducted in a single center with cross-sectional design to all young adults with obesity that worked in Hasan Sadikin General Hospital, Bandung, during August-November 2019. The inclusion was subject with normal ejection fraction (EF) > 50%. We excluded subject with poor echocardiography window, cardiac rhythm other than sinus rhythm, diabetes mellitus, hypertensive heart disease, history of coronary artery disease, congenital heart disease, valvular heart disease, dilated cardiomyopathy, restrictive cardiomyopathy, hypertrophic cardiomyopathy, pericardial disease, myocarditis, heart failure, infection, inflammatory disease , necrotic condition, malignancy, statin consumption, and dyslipidemia. Hs-CRP was measured by particle enhanced turbidimetric assay. Left ventricle function was measured by Global Longitudinal Strain (GLS) with speckle tracking echocardiography technique, performed by 2 independent examiners. The correlation between hs-CRP and GLS was analysed using Pearson correlation. A total of 29 patients (69.0% male, 30.55 + 5,38 years old) included in this study. The average of hs-CRP level was 8.8 (1.07 – 35.1) mg/L and the average of GLS was -19.18 ± 0.72%. After data log transformation of hs-CRP, there was a significant negative correlation (r= -0,542, p=0,001) between the hsCRP and GLS in young adults with obesity. Increasing hs-CRP level may predict subclinical LV systolic dysfunction in obese young adults with no other comorbidities.
Full article

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