Abstract : Children with thalassemia major generally experience growth retardation and metabolic disorders. Stunting is a common feature of children and adolescents with thalassemia. Vitamin D deficiency is associated with the incidence of stunting, yet high levels of ferritin due to multiple blood transfusions and the chelation therapy also have an impact on the incidence of stunting. This study aims at determining the association between vitamin D levels, ferritin and nutritional intake with the height of stunted children with thalassemia major. This cross-sectional study involved 84 thalassemia major children aged 4-14 years taken through consecutive sampling. Among these children with thalassemia major, 34% were stunted children and 42% were severely stunted. Most had ferritin levels of 1000 mg/dL (94.1%) and only 4 children (4.8%) had vitamin D insufficiency. The average energy intake was 1538.7 Kcal/day (70.1% of requirement), protein 45.5 g/day (54.9% of requirement), fat 69.4 g/day (78.6% of requirement), carbohydrate 204.8 g/day (68.1% of requirement), and vitamin D 2.4 µg/day (15.7% of requirement). Based on the Spearman Rank correlation test, there was no significant association between vitamin D and ferritin levels with height for age (p> 0.025), while energy and fat intake were significant association with height for age (p <0.025).
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Abstract : Propolis is a promising natural product that have been widely studied and investigated for health and medical benefits. It appears as a sticky, greenish-brown compound found on the trees and evergreens formed by the sap, bee discharges and bees wax. Propolis is used to line the beehives. The high content of flavonoids in propolis has contributed tremendously to the traditional use of propolis for many illnesses. The variation in chemical and biological composition is due to the type of propolis and locations of the source. Various methods have been used for propolis optimization based on its chemical and biological properties. The side effects of chemical drugs and toxicity is one of the reasons a natural product like propolis is gaining popularity to treat various medical conditions. Propolis has been investigated for its anti-bacterial, anti-fungal, anti-tumor, antidiabetic, and as a treatment for allergy, bronchial asthma and gastric disorders. The promising results from these research areas have paved the way to characterize propolis and elucidate the pathways to explain its mechanism of action. This review will highlight propolis production, its chemical and biological composition and its main biological functions; with a special focus on propolis as a wound healing agent.
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Abstract : IV negative needleless Connector is a device that is connected to the hub of the Central Venous Catheter (CVC) and allows intermittent access to a vascular access device with an administration set or syringe without the use of needles. It is designed to have a negative pressure that could affect the CVP measurements. The purpose of this study was to compare CVP readings before and after the connection of the needleless connector to the CVC and how much does it affect CVP readings for adult ICU patients. A prospective observational study was conducted in a 21-bed in a tertiary referral hospital in Dammam, Saudi Arabia. The study started in November 2017 until July 2019. Participants were older than 18 years with central venous catheters on continuous CVP monitoring in adult critical care unit. During the study period (20 months) the first CVP reading before connecting the needleless connector and the second CVP reading were measured after connecting a sterile needleless connector to the CVC distal lumen while the time difference between every two CVP measurements (Pre and post) was 5-10 minutes. Data were analyzed using IBM SPSS version 24. Total participants were 110 patients, among which 62 (56.36%) where male and 48 (43.64%) were female. The average BMI was 20%. Paired t test showed statistical difference between the two readings before and after the connection respectively: (m± [SD]) (10.85± [4.38] vs. 11.8± [4.06], p ˂0.001). IV Negative needleless connector a significantly increased the central venous pressure measurements of adult ICU patients. This might lead to unnecessary additional diagnostic procedures. Using of IV neutral needleless connector with zero fluid displacement IV connectors might be considered for CVP measurements; however further research is warranted.
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Abstract : Vascular endothelial growth factor (VEGF) induces proliferation of endothelial cells, stimulates angiogenesis, and increases vascular permeability, but information about its role in bone remodeling therapy is limited. The aim of this study is to determine Evaluation of the expression of macrophage colony- stimulating factor (M-CSF) to assessment for dental tissue response includes (periodontal ligament, cementum, alveolar bone) to application of LLLT and VEGF in orthodontic treatment in experimental rabbits. Immunohistochemical study for osteoblastogenesis and osteoclastogenesis include the followings Evaluation of the expression of tissue nonspecific alkaline phosphatase (ALPs) by osteoblast. Evaluation of the expression of collagen type 1 Evaluation of the expression of macrophage colony-stimulating factor (M-CSF) to assessment for dental tissue response includes (periodontal ligament, cementum, alveolar bone) to application of LLLT and VEGF in orthodontic treatment in experimental rabbits.
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Abstract : In this study, fifty isolates of S. marcescens were isolated from Blood, wound, Sputum and urinary tract infections, the results of screening the highest and best bacterial isolates for producing prodigiosin pigment was done and the isolate (SKT14) gave the highest pigment production. Prodigiosin pigment was extracted using ethyl acetate and acetone , Purification was done by using column chromatography , Minimum inhibitory concentration method was used to evaluate the inhibitory effect of purified prodigiosin pigment and the result showed that MIC was 1.56 μg/ml against Enterobacter sp , 25 μg/ml against S. marcescens and 50 μg/ml against S.aureus , as well as by using turbidity method the highest inhibition rate at concentration 50 μg/ml was seen against S. aureus and Enterobacter sp. , moderate against E.coli , while the lowest inhibition rate was against K.pneumoniae and S.marcescens , while highest inhibition rate at concentration 1.56 μg/ml was seen against S. aureus and E.coli , moderate against Enterobacter sp. and S.marcescens , while the lowest inhibition rate was against K.pneumoniae.
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