Abstract : Coumarin-based drugs are widely used to treat thrombotic disorders. The presence of coumarin in plant extracts can be explored to provide alternative treatments to such diseases. This study investigated the effect of Bambusa blumeana leaf extracts using Prothrombin Time (PT) and International Normalized Ratio in vitro using plasma derived from 10 healthy participants (5 male, 5 female). Extracts of varying concentration (25 mg/mL, 50 mg/mL, and 100 mg/mL), a negative control (0 mg/mL) and a positive control (warfarin = 0.016 mg/mL) were used as treatments in the study. Values for PT and INR were recorded by a coagulation analyzer. The minimum values for INR and PT, 0.95 and 11 respectively, were exhibited by the negative control. The maximum values for INR and PT were exhibited by the positive control: 1.58, 17.9 sec respectively. The results of the study show dose-dependent effects among the concentrations of extracts and the PT. Kruskal-Wallis test (p<0.001) confirms a significant difference among extracts (25 mg/mL, 50 mg/mL, 100 mg/mL) and the negative control (0 mg/mL) in both INR and PT. Post-hoc pairwise comparison revealed 100mg/mL as the optimum concentration, p<.001. Mann Whitney U test (p=0.678 for INR and p=0.862 for PT) determined no significant difference with the optimum extract concentration (100 mg/mL) and the positive control (warfarin = 0.016 mg/mL). Future research may investigate the effect of higher concentrations of both the extracts and the positive control and their effect on the optimum concentration of Bambusa blumeana..
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Abstract : Cancer therapy failure is mostly caused by metastases (the spread of cancer cells from where they formed to another place in the body) which in some cases is due to cancerous cells being resistant to therapy. This results in mutations in the genomic makeup of the cancerous cells. Cyloruthenium complexes have been implemented in cancer therapy to help overcome drug resistant cancerous cells and to reduce the toxicity effect of therapy on the host. Ruthenium arene PTA compounds such as RAPTA- C have since been discovered and are used in cancer therapy as they portrayed positive results, while other ruthenium complexes are still going through the clinical trial stage. Herein, this literature review explores the synthesis of cycloruthenated complexes, their role in cancer therapy and drug-resistant tumors..
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Study on deep removal of F- from water by lanthanum-based bio-hybrid materialsStudy on deep removal of F- from water by lanthanum-based bio-hybrid materialsStudy on deep removal of F- from water by lanthanum-based bio-hybrid materialsStudy on deep removal of F- from water by lanthanum-based bio-hybrid materialsStudy on deep removal of F- from water by lanthanum-based bio-hybrid materialsStudy on deep removal of F- from water by lanthanum-based bio-hybrid materialsStudy on deep removal of F- from water by lanthanum-based bio-hybrid materialsStudy on deep removal of F- from water by lanthanum-based bio-hybrid materialsStudy on deep removal of F- from water by lanthanum-based bio-hybrid materialsStudy on deep removal of F- from water by lanthanum-based bio-hybrid materialsStudy on deep removal of F- from water by lanthanum-based bio-hybrid materials

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Abstract : Acquired cystic kidney disease (ACKD) is characterized by small cysts distributed throughout the renal cortex and medulla of patients with ESRD unrelated to inherited renal cystic diseases. Its prevalence and severity are higher in men than in women [7:1] and increase with the duration of azotemia. Children are also prone to the development of ACKD. The study was cross sectional in nature & was undertaken to study the prevalence of cystic changes in patients with chronic kidney disease on maintenance hemodialysis in tertiary care hospital over a period of one year. Radiological imaging was done using Computerized tomography. CT KUB / plain was done for patients to look for acquired renal cysts. Kidney size, the number of cysts & size of cysts as seen by CT KUB were noted The modified Bosniak classification. Analysis of the data was performed using statistical package for the social sciences (SPSS) software. Out of the 50 patients who underwent imaging 32 patients i.e 64% (22 males &10 females) had cystic changes representing presence of one or more cysts, where as 18 i.e 32%, (16 males & 2 females) did not show any cysts. R-Square statistic is 0.335, which is good, indicating that 33.5% of the total variance is explained by best fitting linear regression equation. The model itself is significant at 99.9% as indicated by F-Statistic from ANOVA (in the subsequent table). Overall, this indicates that there is indeed a strong relation of the variables with average number of cysts. Cystic changes, as defined by presence of one or more cysts in one or both kidneys are common (64%) in CKD V patients on maintenance hemodialysis. Acquired cystic kidney disease, as defined by the presence of 4 or more cysts in each kidney is relatively not as common..
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Abstract : The aim of this study was to determine the prevalence of musculoskeletal disorders amongst teachers in the UAE, and further extend to examine the association of musculoskeletal disorders in teachers in the UAE with a) Socio-demography, b) work, c) social, d) psychological factors and to assess predictors of musculoskeletal disorders amongst teachers. The Nordic Musculoskeletal Questionnaire (NMQ) and A validated questionnaire containing questions of predictors was distributed to teachers of four schools in Ajman and Dubai and 371 teachers responded. The most common site of pain reported was neck pain at 43.7% for 12-month history and 24.5% for 7 days, followed by lower back pain at 42.6% in the last 12 months and 24.1% in the last 7 days. Musculoskeletal pain was more prevalent among female gender, higher body mass index (BMI), more than 7 years of work, and with self-reported anxiety, depression, and high work stress. Musculoskeletal spinal pain such as neck and back pain among teachers was highly prevalent and risk factors associated were age, gender, BMI, years of work, regular exercise, hours of sleep, depression, and stress..
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