International Medical Journal (ISSN:13412051)

Aim and Scope

Aim-

International Medical Journal ISSN: (13412051) is an international open-access journal publishes twelve times each year. The "International Medical Journal" is a peer-reviewed, monthly, online international research journal, which publishes original articles, research articles, review articles with top-level work from all areas of Medical Science Research and their application including Aetiology, bioengineering, biomedicine, cardiology, chiropody, ENT etc. Researchers in all Medical Science and Pharmacy fields are encouraged to contribute articles based on recent research. Journal publishes research articles and reviews within the whole field of Medical Science and Pharmacy Research, and it will continue to provide information on the latest trends and developments in this ever-expanding subject. International Medical Journal journal covers almost all disciplines of Medical Science and Pharmacy. Researchers and students of M.B.B.S, M.D., D.T.C.D., GYNE., M.S., M.Pharma, And PhD are requested to send their original research articles to International Medical Journal. Changjiang Liuyu Ziyuan Yu Huanjing/Resources and Environment in the Yangtze Valley Shenyang Jianzhu Daxue Xuebao (Ziran Kexue Ban)/Journal of Shenyang Jianzhu University (Natural Science) General Medicine (ISSN:1311-1817) Chinese Journal of Evidence-Based Medicine Zhongguo yi liao qi xie za zhi = Chinese journal of medical instrumentation Lizi Jiaohuan Yu Xifu/Ion Exchange and Adsorption

Scope-

International Medical Journal ISSN: (13412051) is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:

Anatomy Physiology Biochemistry Pharmacology
Pathology Forensic medicine Microbiology Community Medicine
Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology
Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases
Anaesthesia Cancer research Neurosurgery Orthopedics

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Latest Journals
International Medical Journal
Journal ID : IMJ-13-08-2021-884
Total View : 444

Abstract : To estimate IgE and histamine levels in patients with drug allergy and with past history of drug allergy. Compare these levels with that of normal individuals. Assess the association of demographic factors, nature of drugs and clinical presentation with IgE and histamine levels. 113 potential participants were totally interviewed. 66 selected based on selection criteria. 22 had current allergy (CA), 22 past history of allergy (PA) and 22 without any allergy (NA). Study was initiated after getting IHEC approval and informed consent from each participant. Estimation of serum IgE and histamine was done using ELISA kits. Demographic details, details of drugs and clinical presentation were recorded. Time interval between onset of allergy and estimation of IgE and histamine was recorded for patients with PA. Results were analyzed using ANOVA and student t test. p<0.05 was considered significant. IgE and histamine levels were significantly higher in CA compared to NA and PA subjects. Normal mean level IgE was 72.6 IU/ml and histamine 42.53 ng/ml. In PA levels were higher than that of NA but lower than CA. Males and civil workers had a higher level than females. Age related difference in the levels was not observed. NSAIDs induced allergy resulted in maximum elevation of IgE (538.74 IU/ml) and histamine (158.32 ng/ml) followed by antimicrobials (IgE 395.97 IU/ml) and histamine (133.42 ng/ml). Patients who developed maculopapular rashes had maximum level of IgE (627.87 IU/ml) and histamine (182.25 ng/ml). The time dependent decline in both the levels was observed in PA. Higher IgE level was associated with higher level of histamine in all the groups. CA, NSAIDs and maculopapular rashes resulted in maximum elevation of IgE and histamine. In PA, IgE level was higher than NA group. Whether estimation of IgE would indicate past allergy or the tendency to develop allergy has to be assessed by further studies..
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International Medical Journal
Journal ID : IMJ-12-08-2021-882
Total View : 446

Abstract : This study aimed to investigate the effect of COVID-19 on pulmonary function tests after 6-8 weeks of recovery, to confirm the necessity of the test to follow up the patients after recovery and to find out the possibility to use it as a workable procedure to indicate the severity of the previous infections. This a randomized-control study The study was conducted in Basrah City. Three groups of patients were divided based on the severity of the previous infection, Group 1 included the patients with previously severe infection; group 2 were the patients with previously mild infection and group 3 who never infected. Pulmonary function tests(PFTs) were measured in all groups using a spirometer. Data analysis showed that group 1 had a significant change in some PFT,6-8 weeks after recovery and this change was in form a restrictive pattern, while group 2 showed non- significant changes compared to group 3. COVID-19 might affect PFT after recovery in a way depended on the severity of the infection. This study pointed to the necessity of following up the previously infected patients and that measurement was workable test to indicate the severity of the previous infection..
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International Medical Journal
Journal ID : IMJ-12-08-2021-881
Total View : 425

Abstract : Vertebrobasilar insufficiency (VBI) mainly affects elderly people and involves reduced blood flow in the posterior part of the brain. The vertebrobasilar (VB) flow system is also called the posterior circulation, comprising the vertebral arteries, basilar artery, and posterior cerebral arteries and their branches, supplying the brainstem, thalamus, hippocampus, cerebellum, and regions of the occipital and temporal lobes. Dementia is the outcome of the Vertebrobasilar insufficiency that can be proved as lethal source for life. In this affected person loose the senses of maturity, reasoning for life and whatever is happening in the state of livings. To determine the association between vertebrobasilar insufficiency and mixed dementia in geriatric population. Analytical cross sectional study was conducted to determine association between vertebrobasilar insufficiency and mixed dementia. Sample of 135 elderly people was taken from different Neuro- centres in Lahore. VBI test of the participants was done. Mini-Mental State Examination of dementia Levels was evaluated. 23% were having positive VBI test. 77% were negative. 51.9% were having mild dementia, 25.9% were having moderate dementia, 14.1% were having no dementia and 8.1% were having severe dementia. Mean MINI-MENTAL STATE EXAMINATION Score was found 21 out of total 30 with SD±5.4. Higher score indicates lower dementia. P value indicates that there is significant association between VBI test and MINI-MENTAL STATE EXAMINATION (P value .000) This study concluded that there is significant association between VBI test and MINI-MENTAL STATE EXAMINATION..
Full article
International Medical Journal
Journal ID : IMJ-10-08-2021-879
Total View : 9

Abstract :

Osteoporosis is the major problem worldwide. Though it affects both the gender, women are the most commonly affecting group due to their physiological differences. This study protocol is designed to evaluate the effect of lifestyle modification intervention programme on quality of life, bone health status, physical function capacity and medication adherence among postmenopausal women with osteoporosis. A mixed Method approach adopting a Sequential explanatory design is proposed for this study. The study will be carried out in two phases. The randomized control trial in the phase 1 includes postmenopausal women of age group 45-65 years with the Bone mineral density scores between -1 and -3. The participants are further categorized into experimental and control group. The experimental group will receive interventions on lifestyle modifications whereas control group will continue with the standard care. Quality of life is the primary outcome measure and bone mineral density; physical functional capacity and the medication adherence are the secondary outcome measures. Follow up is done at 3 months and 6 months followed by that qualitative data from the sub-sample of the main sample related to the experiences living with osteoporosis while undergoing the Lifestyle Modification Intervention Program will be collected in phase 2. If the lifestyle modification in this study shows positive outcomes, it may be amalgamated in standard patient care. Since pharmacological therapies often have the risk of side effects and are expensive, more complications can be avoided if patients adopt lifestyle changes as their way of life.

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International Medical Journal
Journal ID : IMJ-10-08-2021-875
Total View : 459

Abstract : Oral submucous fibrosis [OSMF] is a potentially malignant disorder of oral cavity. The epidemiology of OSMF strongly suggests an individual susceptibility which could be cytokine based, especially as the initial feature of OSMF is chronic inflammation accompanied by chronic fibrosis. Cytokines can act as Prognostic tools for detecting malignant transformation of oral potentially malignant disorders. It has been evident that different cytokines are expressed by dysplastic cells, the most common of which include tumour necrosis factor alpha [TNF-α], IL-1, IL-6, and IL-8. To assess the Serum levels of IL- 1 beta, and IL-6 in oral submucous fibrosis patients. This study group comprised 75 individuals divided into 3 groups GROUP A with 25 and GROUP B with 25 OSMF individuals, GROUP C 25 healthy individuals as controls. Serum levels of IL-1β, IL-6 were measured using enzyme linked immunoassay kits in all the subjects. The present study showed a significant rise in serum levels of IL-1beta and IL-6 levels in OSMF patients in contrast to the control group with the significance of p-value [<0.05]. Proinflammatory cytokines IL-1β and IL-6 were elevated, might act as a diagnostic and prognostic marker in oral submucous fibrosis patients..
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