International Medical Journal (ISSN:13412051)

Aim and Scope

Aim-

International Medical Journal ISSN: (13412051) is an international open-access journal publishes twelve times each year. The "International Medical Journal" is a peer-reviewed, monthly, online international research journal, which publishes original articles, research articles, review articles with top-level work from all areas of Medical Science Research and their application including Aetiology, bioengineering, biomedicine, cardiology, chiropody, ENT etc. Researchers in all Medical Science and Pharmacy fields are encouraged to contribute articles based on recent research. Journal publishes research articles and reviews within the whole field of Medical Science and Pharmacy Research, and it will continue to provide information on the latest trends and developments in this ever-expanding subject. International Medical Journal journal covers almost all disciplines of Medical Science and Pharmacy. Researchers and students of M.B.B.S, M.D., D.T.C.D., GYNE., M.S., M.Pharma, And PhD are requested to send their original research articles to International Medical Journal.

Scope-

International Medical Journal ISSN: (13412051) is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:

Anatomy Physiology Biochemistry Pharmacology
Pathology Forensic medicine Microbiology Community Medicine
Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology
Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases
Anaesthesia Cancer research Neurosurgery Orthopedics

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Latest Journals
International Medical Journal
Journal ID : IMJ-05-01-2022-1150
Total View : 475
Title : Correlation of Salivary LDH with Histopathological Grade of Head and Neck Cancers
Abstract : Salivary diagnostics boasts increased accessibility, accuracy and affordability as a diagnostic modality and is safer for patients and healthcare workers compared to pre-existing modalities. Progressive increase in LDH levels are seen to be positively related to the degree of cellular atypia and can be used as a screening tool in assessing the malignant potential of premalignant lesions. Whereas its positive relationship with histological differentiation can be used as a prognostic indicator in malignancies. To study the correlation between salivary Lactate dehydrogenase (LDH) in Head and neck cancer (HNC) with the histopathological grade. Patients who were biopsy proven to have head and neck cancers, were planned for appropriate surgery based on staging and histopathology. Their preoperative salivary LDH and post-operative salivary LDH was measured to look for any change in values to prove a correlation between malignancy and salivary LDH levels and was compared with the histological grade. The grade of differentiation directly corresponds to the salivary LDH levels, with a statistically significant p value=0.0008. Stage wise preoperative salivary LDH shows statistically significance with p-value= 0.013 along with a statistically significant fall post- operatively (p-value=0.018) and at 6 months (p-value=0.046). Poorer the differentiation higher the Salivary LDH levels. There is a possible prognostic role of salivary LDH in head and neck malignancies which needs to be considered as an alternative or adjunct to traditional biopsy..
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International Medical Journal
Journal ID : IMJ-04-01-2022-1149
Total View : 435
Title : Comparison vacuum -assisted closure system and conventional dressing on wound healing in patient with leg ulcer
Abstract :

One of the most common causes for admission in surgical ward is non healing ulcer. In which diabetes is the most common etiology. In most of the cases, hospital stay of many weeks is required for management of the above. In many cases they ultimately go for amputation. Acute and chronic wounds affect at least 1% of the population. In all sense patients turns to be a burden for society and family. Vacuum assisted closure is a universally accepted method for dressing. It has proved its efficacy for wound dressing. Faster wound healing, shorter hospital stay.Still in our hospital, majority of dressings are conventional our aim is to show the advantage of V.A.C over conventional dressing in our hospital on wound healing. Total 50 patients were enrolled They are divided in to two groups one for conventional dressing group Department of general surgery , Dr D YPatil medical college , hospital and research center , Pimpri, Pune, Dr D Y Patil vidyapeeth, Pune and the other for VAC.Out of 50 patients 25 patients got the VAC dressing done and 25 conventional dressing. Significant reduction in ulcer size was noted in patients with VAC dressing as compared to conventional dressing.VAC therapy is a contemporary technique  for the treatment of wounds. Its introduction has transformed the path of wound care. Based on the findings from the present study and other studies available, VAC assisted wound care results in improved wound healing ( reduction in wound size and formation of healthy granulation) and at a faster rate.

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International Medical Journal
Journal ID : IMJ-04-01-2022-1148
Total View : 486
Title : The study on prevalence of eosinopenia and lymphopenia in covid-19 patients and its importance in predicting the disease severity – a retrospective observational study
Abstract : Early detection of COVID 19 is necessary as it has caused increased global mortality along with a variety of manifestations and rapid progression. There are many markers of COVID 19 viral pneumonia but the exist a few predictors of its severity. To observe the prevalence and importance of Eosinopenia and Lymphopenia in predicting severity of COVID-19 cases. The current study involved 81 cases of COVID 19 viral pneumonia of which 40 were classified as mild while 41 were severe requiring ICU care. The relatability between the lymphocyte and eosinophil count of the admitted patients, for severity and outcome of the disease was analysed using statistical analysis software. Among the study participants, 41 were severe cases which required ICU care and 40 were mild cases which required ward care. Out of the 41 severe cases, all 41 patients (100%) were found to have eosinopenia while 28 patients (68.3%) were found to have lymphopenia. Additionally, among the severe cases, 28 patients (68.3%) were found to have both eosinopenia and lymphopenia. A significant association was also found between lymphopenia and Acute Kidney Injury. A significant association was also observed between the presence of eosinopenia, lymphopenia and both simultaneously, and mechanical ventilation. In this study it was found that eosinopenia and lymphopenia can be considered as a marker of severity of COVID 19, thus if admission sample of Complete blood count shows eosinopenia or lymphopenia, such patients must be given vigorous treatment as probability of worsening of clinical condition is higher..
Full article
International Medical Journal
Journal ID : IMJ-04-01-2022-1146
Total View : 375
Title : Effect of the solvent concentration and pH on polyphenol, chlorophyll content, and antioxidant activity of Hydrocotyle asiatica grown in Southern Center, Vietnam
Abstract : The impact of extraction condition of antioxidant polyphenol and chlorophyll from species Hydrocotyle asiatica grown in Vietnam was presented in the current study. The extraction condition was studied composed of solvent concentrations (60 to 100 with jump step (δ) of 5) and solvent pH (2 to 10 with δ of 1). Besides the content of polyphenol and chlorophyll, the target function of antioxidant activity was also evaluated based on total antioxidant activity and reducing power activity. The results showed that polyphenol and chlorophyll content and antioxidant activity from Hydrocotyle asiatica were affected by the solvent concentration and solvent pH significantly (p<0.05). The content of polyphenol (3.958±0.028 mg gallic acid equivalent/g DW) and chlorophyll (2.412±0.057 mg/g DW), and the antioxidant activity composed of total antioxidant activity (2.077±0.022 mg ascorbic acid/g DW) and reducing power activity (11.366±0.53 mg FeSO4 equivalent/g DW), was the highest at 95% ethanol and solvent (pH 5), compared to other conditions. Polyphenol, chlorophyll content, and antioxidant activity were changed according to the model of level 2 under the impact of solvent concentration and solvent pH. The results were valuable in the antioxidant polyphenol and chlorophyll extraction for applicating functional food and pharmaceuticals..
Full article
International Medical Journal
Journal ID : IMJ-04-01-2022-1145
Total View : 363
Title : Stress Response Evaluation in Sahel Bucks Following Incisional Wounds Closure with N-butyl Cyanoacrylate and Nylon: A Study on Serum Cortisol
Abstract : Surgical stress is an immediate aftermath of most surgical procedures which may directly/indirectly prolong recuperation and healing process of the animal. More stress response also emanates from the type of suture material and pattern used for the incision closure. Researchers are looking for materials that can lessen this stress. Serum cortisol measurement is one of the reliable markers of stress response. With the introduction of medical grade cyanoacrylate into clinical practice as a skin closure material, a number of promising outcomes have been reported by some researchers and its potential alternative to conventional sutures. This study evaluates surgical stress response in skin incisions closed with N-butyl Cyanoacrylate and Nylon while monitoring serum cortisol levels in Sahel bucks. Ten clinically healthy bucks (male goats) with mean age of 9.7±1.33 months with mean weight 13.2±1.31kg were randomly separated into two groups (A and B) of five bucks each. The bucks were prepared for surgery and skin incisions made were closed using N-butyl Cyanoacrylate and Nylon for group A and B respectively. Blood samples were taken before and after the procedure at 0, 5, 8, 24, 48 and 72 hours where serum cortisol levels were quantitatively evaluated. Serum cortisol levels were seen to rise in incisions closed with Nylon compared to those closed with N-butyl Cyanoacrylate..
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