International Medical Journal (ISSN:13412051)

Aim and Scope

Aim-

International Medical Journal ISSN: (13412051) is an international open-access journal publishes twelve times each year. The "International Medical Journal" is a peer-reviewed, monthly, online international research journal, which publishes original articles, research articles, review articles with top-level work from all areas of Medical Science Research and their application including Aetiology, bioengineering, biomedicine, cardiology, chiropody, ENT etc. Researchers in all Medical Science and Pharmacy fields are encouraged to contribute articles based on recent research. Journal publishes research articles and reviews within the whole field of Medical Science and Pharmacy Research, and it will continue to provide information on the latest trends and developments in this ever-expanding subject. International Medical Journal journal covers almost all disciplines of Medical Science and Pharmacy. Researchers and students of M.B.B.S, M.D., D.T.C.D., GYNE., M.S., M.Pharma, And PhD are requested to send their original research articles to International Medical Journal.

Scope-

International Medical Journal ISSN: (13412051) is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:

Anatomy Physiology Biochemistry Pharmacology
Pathology Forensic medicine Microbiology Community Medicine
Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology
Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases
Anaesthesia Cancer research Neurosurgery Orthopedics

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Latest Journals
International Medical Journal
Journal ID : IMJ-10-02-2020-224
Total View : 256

Abstract : The present study aimed to assess self-care management of patients with heart failure in king Khaled hospital in Najran city southern kingdom of Saudi Arabia. A descriptive cross-sectional study design was conducted on 52 patients with heart failure admitted to the king Khaled hospital - cardiac department .data were collected to assess self-care management which regarding to compliance of treatment medication, sodium, restriction of fluid, take weights daily, practice regular exercises, and keeping appointment. The data were collected from all patients and the analyzed using SPSS version 23 software. The result of present study revealed that of 52 patients’ compliance ranged between 9.6% and 86.5 % of the patients. the high rate of compliance was found in Keeping follow-up appointments 45(86.5) % and take your medications exactly   as directed 43 (65.3%). The highest rates of non-compliance are found in fluid restriction 47(90.3%) , and exercise 40(76.9%) ,and  follow a low sodium diet 30 (57.7%). The present study shows that knowledge deficit is seem the most important reason of poor self-care management, lack of knowledge to avoid drinking excess fluids 46 (88.5%), lack of knowledge to comply with the dietary High in potassium, 43(82.6%) and lack of knowledge   to weight myself daily 37(71.1. The result of the present study concluded that low knowledge of the patients about their illness which reflect on poor self-care of HF patient.
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International Medical Journal
Journal ID : IMJ-10-02-2020-223
Total View : 139

Abstract : Oxidative stress is a status that can prevent people from suffering from diseases including cancer. The 8-hydroxydeoxyguanosine (8-OHdG) is a marker that reflects oxidative DNA damage in the body.  In this study, Traganum nudatum plants were investigated for their potential to protect cellular DNA from oxidative damage by evaluating 8-OHdG assays in cultured human lymphocytes by incubated in ethanol extract of Traganum nudatum (0.05, 0.1, 0.5, 1 and 2.5 mg/mL).  White Blood samples were taken from healthy volunteers and lymphocytes were isolated. The lymphocytes were then incubated in aqueous and ethanol extract of rosemary (0, 10, 100 and 1000 µg/ml). The obtained extracts at 10,100 and 1000µg/mL from aerial parts ethanolic extracts of Traganum nudatum significantly decreased the levels of 8-OHdG (P < 0.01). suggesting their usefulness as protective agents against oxidative DNA damage and offering pharmacological credibility to the ethnomedical traditional usage of the plant in medicine, modifying its beneficial application against free-radical-induced diseases.
Full article
International Medical Journal
Journal ID : IMJ-10-02-2020-222
Total View : 275

Abstract : There is a growing evidence linking the autonomic nervous system with various physiological and pathological states. The changes in heart rate (HR) rely on a balance between the influence of the parasympathetic and the sympathetic branches of the autonomic nervous system (ANS) on the heart. There are few researches on effect of BMI and heart rate variability (HRV). A case-control study (120 participants; 60 preelamptic and 60 control) were conducted at Omdurman Maternity Hospital and Saad Abul Ela Maternity Hospital - Sudan, during the period from June 2015 to December 2016. Medical, obstetrics history and clinical examination were performed to all studied women guided by prearranged questionnaires. Cardiac autonomic modulation (CAM) of the heart was examined in both studies based on HRV indices, namely, the natural logarithm (Ln) of the standard deviation of the NN intervals (LnSDNN), the square root of the mean squared differences of successive NN intervals (LnRMSSD), total power (LnTP), very low frequency (LnVLF), low frequency (LnLF) and high frequency (LnHF). Also, normalized low frequency (LF Norm) and high frequency (HF Norm) and LnLF/HF ratio were measured. The study demonstrated that in the normal weight group, women with preeclampsia had significantly higher LnSDNN, LnVLF and LnLF [P > 0.05]. Also, there was no significant difference in the HRV measurements between overweight and obese groups of the women with preeclampsia as well as the controls. The study revealed that preeclampsia could occur in the absence of obesity.
Full article
International Medical Journal
Journal ID : IMJ-09-02-2020-219
Total View : 152

Abstract : Lupus nephritis (LN) is diagnosed by presence of proteinuria (0.5g per day or a dipstick score of > 3+) or red cell casts on microscopic urine analysis. Assessing histological severity and chronic lesions in LN is by renal biopsy. However, it is invasive and repeated biopsies are needed in monitoring treatment of LN. Therefore, new biomarkers for early diagnosis of lupus renal disease have to be searched. To evaluate urinary platelet factor4 (PF4) and vascular cell adhesion molecule-1(VCAM-1) as early markers of lupus nephritis. 120 patients with systemic lupus erythematosus (SLE) were involved and classified into 3 main groups; group I included 40 patients with inactive SLE, group II included 40 patients with active SLE without lupus nephritis and group III included 40 patients with active SLE with lupus nephritis. All patients were submitted to; urine analysis, complete blood count, fasting blood glucose, serum creatinine, liver function tests, serum complement 3, antinuclear antibody, anti-double stranded DNA level and urinary PF4 and VCAM-1 levels assays. Urinary PF4 and VCAM-1 levels were significantly higher in lupus nephritis group than in the other two groups. The cutoff value of PF4 in prediction of active lupus with nephritis is ≥7.93pg/ng with sensitivity 100% and specificity 90.5% and that of VCAM-1 is ≥783pg/ng with sensitivity 100% and specificity 93.8%. Urinary platelet factor 4 and vascular cell adhesion molecule-1 can serve as early markers for identifying LN.
Full article
International Medical Journal
Journal ID : IMJ-09-02-2020-218
Total View : 132

Abstract : Ischemic cardiomyopathy is the most frequent etiology of heart failure with reduced ejection fraction (HFrEF) and a result of ventricular structural, functional, and electrical remodelling. T peak to end (Tpe) interval is an electrocardiographic parameter that represent repolarization heterogeneity and had prognostic value for ventricular arrhythmia. Patients with Ischemic cardiomyopathy face a significant burden of arrhythmias. Mechanical dispersion is a functional remodelling parameter that can be measured by time to peak longitudinal strain using speckle tracking echocardiography. This study aims to assess the relationship between Tpe interval with time to peak longitudinal strain in ischemic cardiomyopathy patients. This study was conducted with observational analytical cross-sectional design. Ischemic cardiomyopathy subjects were included at Dr. Hasan Sadikin General Hospital, Bandung, from August to October 2019. Tpe interval was measured manually with tangential method. Time to peak longitudinal strain was measured using speckle tracking echocardiography. The correlation between Tpe interval and time to peak longitudinal strain was analyzed using Pearson correlation. A total of 30 subjects were included in this study. The average age was 58 ± 8 years old and the average left ventricular ejection fraction was 27 ± 5.5%. The average of Tpe interval was 83.4 + 7.62 ms and the average of time to peak longitudinal strain was 93.13 ± 34.51 ms. The Pearson correlation test showed a significant weak positive correlation (r=-0.386, 95% CI (0.029 – 0.743, p 0.018) between Tpe interval and time to peak longitudinal strain in ischemic cardiomyopathy patients. There was a significant weak positive correlation between Tpe interval and time to peak longitudinal strain in ischemic cardiomyopathy patients.
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