International Medical Journal (ISSN:13412051)

Aim and Scope

Aim-

International Medical Journal ISSN: (13412051) is an international open-access journal publishes twelve times each year. The "International Medical Journal" is a peer-reviewed, monthly, online international research journal, which publishes original articles, research articles, review articles with top-level work from all areas of Medical Science Research and their application including Aetiology, bioengineering, biomedicine, cardiology, chiropody, ENT etc. Researchers in all Medical Science and Pharmacy fields are encouraged to contribute articles based on recent research. Journal publishes research articles and reviews within the whole field of Medical Science and Pharmacy Research, and it will continue to provide information on the latest trends and developments in this ever-expanding subject. International Medical Journal journal covers almost all disciplines of Medical Science and Pharmacy. Researchers and students of M.B.B.S, M.D., D.T.C.D., GYNE., M.S., M.Pharma, And PhD are requested to send their original research articles to International Medical Journal. Changjiang Liuyu Ziyuan Yu Huanjing/Resources and Environment in the Yangtze Valley Shenyang Jianzhu Daxue Xuebao (Ziran Kexue Ban)/Journal of Shenyang Jianzhu University (Natural Science) General Medicine (ISSN:1311-1817) Chinese Journal of Evidence-Based Medicine Zhongguo yi liao qi xie za zhi = Chinese journal of medical instrumentation Lizi Jiaohuan Yu Xifu/Ion Exchange and Adsorption

Scope-

International Medical Journal ISSN: (13412051) is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:

Anatomy Physiology Biochemistry Pharmacology
Pathology Forensic medicine Microbiology Community Medicine
Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology
Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases
Anaesthesia Cancer research Neurosurgery Orthopedics

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Latest Journals
International Medical Journal
Journal ID : IMJ-20-05-2022-1448
Total View : 486
Title : Vitamin D3 levels in patients with Pulmonary tuberculosis- A cross-sectional study.
Abstract : Pulmonary Tuberculosis (PTB) is a chronic infectious disease caused by Mycobacterium tuberculosis. Vitamin D3 is a secosteroid that has pleiotropic effects on many organs, including the adaptive immune system and the innate immune system. It is a potent immunomodulator of innate immune responses by acting as a cofactor for induction of anti-mycobacterial activity [6]. Vitamin D3 deficiency is generally prevalent in pulmonary tuberculosis patients. Hence, we extended our study to analyze the changes in the level of vitamin D3 in various subgroups of PTB patients which includes newly diagnosed sputum positive PTB; Recurrent PTB; PTB in patients with Diabetes mellitus and PTB patients who lost to follow up. A cross-sectional study was conducted among 95 sputum positive pulmonary tuberculosis patients over a period of two years in Department of Pulmonary Medicine, SMVMCH, India. Serum Vitamin D3 levels were measured in the study subjects and their levels were compared among the different subgroups. Vitamin D3 deficiency (<10ng/ml) was found in all the subgroups of pulmonary tuberculosis patients with higher prevalence in patients with advanced age, low BMI, farmers, smokers, alcoholics and diabetes. However, difference in Vitamin D3 levels among the patients with newly diagnosed PTB, Recurrent TB and PTB who lost follow up were not statistically significant. Hence, vitamin D3 level has to be assessed in all the pulmonary tuberculosis patients and supplementation of vitamin D3 in patients with deficiency and insufficiency improves the morbidity in these groups of patients..
Full article
International Medical Journal
Journal ID : IMJ-17-05-2022-1444
Total View : 418
Title : Methotrexate-loaded IOL as prophylactic of PCO
Abstract : Postoperative complications of cataract surgery might include posterior capsule opacification (PCO, 8-34.3%). The intraocular lens (IOL), the treatment of choice, has the potential to serve as a prophylactic drug reservoir. PubMed and Google Scholar were used to perform this systematic review. We included articles with inclusion criteria were (1) using only MTX-loaded IOL, (2) published in the last 5 years, and (3) available in full text, in English. Methotrexate-poly(lactic-co-glycolic) acid (MTX-PLGA) showed a significant capability of reducing human lens epithelial cell growth (p<0,001). MTX caused a considerable increase in the time required for the posterior capsule to be completely covered with cells (P=0.046). Over the course of 14 days, it demonstrated an initial concentration peak followed by a steady release of MTX. Modification of IOL as drug delivery can be achieved by coating, soaking, or loading with haptics. Methotrexate's biological effect resulted in a long-term inhibition of cellular proliferation without harming endothelial cells. It also has a similar favorable effect on other fibrotic responses as PCO. PLGA encapsulates and stores a substantial amount of the drug, enabling the development of a slow-release device that delivers the drug continuously. Methotrexate-loaded IOL is a potential treatment in the prevention of PCO after cataract surgery..
Full article
International Medical Journal
Journal ID : IMJ-17-05-2022-1443
Total View : 465
Title : Myositis, Acute Kidney Injury and Hepatitis in Dengue Infection; The dangerous Trio- A Brief Report
Abstract : To estimate the prevalence of myositis and hepatitis in dengue positive patients and their association. This cross sectional study was carried in Acharya Vinoba Bhave Rural Hospital, Sawangi (Meghe), wardha district of central India during the month of June over a period of 3 months. Total 50 serologically diagnosed cases of dengue(NS-1-antigen) fever were included in this study. Participants were divided in 2 groups on bases of Creatinine kinase levels. After detailed history and clinical examination, liver function test, renal function test, Creatinine kinase(CK), creatinine clearance was calculated and urine for myoglobin were sent. Patients were given standard line of management. Out of 50 cases, 25 cases had raised CK levels. And out of those 25 cases, 8 (30%) patients tested positive for myoglobin in urine, (p< 0.05). Presence of myoglobin in urine is an indicator of rhabdomyolysis [1], [2]. Eighty two percent cases had hepatitis with increased SGPT levels, (p<0.05). All patients who had myositis had hepatitis. Twenty-three patients (90%) of 25 patients had raised creatinine levels and decreased creatinine clearance indicating acute kidney injury. All patients with raised CK levels showed hepatitis and evidence of acute kidney injury. Dengue patient should be evaluated for hepatitis and Myositis. Myositis should be predicated early so that acute kidney injury can be prevented. Hepatitis and myositis invariably co-exist and all patient with transaminitis should be evaluated for acute kidney injury and myositis by evaluating CK levels..
Full article
International Medical Journal
Journal ID : IMJ-11-05-2022-1438
Total View : 390
Title : Large aneurysmspuriumofthe dorsalis pedis artery in condition after osteosynthetictreatmentof an upperanklefracture as a very rare complication – case report
Abstract : A case is presented with a post-traumatic aneurysm spurium of the anterior tibia lartery with peripheral partial embolization and severe progressive fore foot ischemia after initial treatmentof a distal upper ankle fracture three days ago. The procedure consisted of diagnosis, oral anticoagulation, Prostavasin infusions, resection of the aneurysm, and placement of a venous interposition device. After regression of the severe ischemi creaction, the ischemia pain was completely regressed and the patient could be discharged without any symptoms..
Full article
International Medical Journal
Journal ID : IMJ-10-05-2022-1434
Total View : 448
Title : Role of Noninvasive Serum biomarkers for the Diagnosis of Liver Fibrosis/Cirrhosis
Abstract : The present study aimed to investigate the diagnostic values of noninvasive markers of liver cirrhosis: the concentrations of the enzymes aspartate transaminase (AST), Alanine Aminotransferase (ALT), total bilirubin, direct bilirubin, indirect bilirubin, gamma-glutamyl transferase, Uric Acid, Total Antioxidant Capacity, Total Oxidant Status and Platelet count with hepatic functional markers indices in patients with cirrhosis of liver in varying etiology. Blood samples of patients suffering from severe liver disease 26 were included. The diagnosis was based on a luminescent immune analyzer and biochemical assays using an automatic biochemical analyzer, to analyze the correlation between the hepatic function and fibrosis markers varying etiology in both the cases and controls. The serum levels of biochemical parameters and liver function tests were significantly higher compare to control (P<0.021): the serum levels of oxidative markers were shown significantly lower compared to healthy controls (P<0.020). The analysis between the liver function and three oxidative stress biomarkers of liver disease positively correlated with AST (P<0.004) and gamma-GT (P<0.001), statistically significant oxidative biomarkers, and diagnostic parameters. The concentration of serological parameters indices changed significantly based on the specific liver cirrhosis etiology, diagnostic parametric tests are positively correlations with hepatic disease. Thus, the detection of these biomarkers might improve the prognosis and diagnosis of liver cirrhosis..
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