International Medical Journal

Aim and Scope

Aim-

International Medical Journal ISSN: (13412051) is an international open-access journal publishes twelve times each year. The "International Medical Journal" is a peer-reviewed, monthly, online international research journal, which publishes original articles, research articles, review articles with top-level work from all areas of Medical Science Research and their application including Aetiology, bioengineering, biomedicine, cardiology, chiropody, ENT etc. Researchers in all Medical Science and Pharmacy fields are encouraged to contribute articles based on recent research. Journal publishes research articles and reviews within the whole field of Medical Science and Pharmacy Research, and it will continue to provide information on the latest trends and developments in this ever-expanding subject. International Medical Journal journal covers almost all disciplines of Medical Science and Pharmacy. Researchers and students of M.B.B.S, M.D., D.T.C.D., GYNE., M.S., M.Pharma, And PhD are requested to send their original research articles to International Medical Journal.

Scope-

International Medical Journal ISSN: (13412051) is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:

Anatomy	Physiology	Biochemistry	Pharmacology
Pathology	Forensic medicine	Microbiology	Community Medicine
Otorhinolaryngology	Internal Medicine	General Surgery	Obstetrics and Gynecology
Radiology	Pulmonary Medicine	Dermatology and Venereal diseases	Infectious Diseases AMA, Agricultural Mechanization in Asia, Africa and Latin America Teikyo Medical Journal Journal of the Mine Ventilation Society of South Africa
Anaesthesia	Cancer research	Neurosurgery	Orthopedics

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International Medical Journal

Journal ID : IMJ-10-02-2020-223

Total View : 141

Title : Protective effects of Traganum nudatum against oxidative DNA damage in human lymphocytes

Abstract : Oxidative stress is a status that can prevent people from suffering from diseases including cancer. The 8-hydroxydeoxyguanosine (8-OHdG) is a marker that reflects oxidative DNA damage in the body. In this study, Traganum nudatum plants were investigated for their potential to protect cellular DNA from oxidative damage by evaluating 8-OHdG assays in cultured human lymphocytes by incubated in ethanol extract of Traganum nudatum (0.05, 0.1, 0.5, 1 and 2.5 mg/mL). White Blood samples were taken from healthy volunteers and lymphocytes were isolated. The lymphocytes were then incubated in aqueous and ethanol extract of rosemary (0, 10, 100 and 1000 µg/ml). The obtained extracts at 10,100 and 1000µg/mL from aerial parts ethanolic extracts of Traganum nudatum significantly decreased the levels of 8-OHdG (P < 0.01). suggesting their usefulness as protective agents against oxidative DNA damage and offering pharmacological credibility to the ethnomedical traditional usage of the plant in medicine, modifying its beneficial application against free-radical-induced diseases.
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International Medical Journal

Journal ID : IMJ-10-02-2020-222

Total View : 277

Title : Heart Rate Variability in Normal Weight, Overweight and Obese Preeclamptic Women

Abstract : There is a growing evidence linking the autonomic nervous system with various physiological and pathological states. The changes in heart rate (HR) rely on a balance between the influence of the parasympathetic and the sympathetic branches of the autonomic nervous system (ANS) on the heart. There are few researches on effect of BMI and heart rate variability (HRV). A case-control study (120 participants; 60 preelamptic and 60 control) were conducted at Omdurman Maternity Hospital and Saad Abul Ela Maternity Hospital - Sudan, during the period from June 2015 to December 2016. Medical, obstetrics history and clinical examination were performed to all studied women guided by prearranged questionnaires. Cardiac autonomic modulation (CAM) of the heart was examined in both studies based on HRV indices, namely, the natural logarithm (Ln) of the standard deviation of the NN intervals (LnSDNN), the square root of the mean squared differences of successive NN intervals (LnRMSSD), total power (LnTP), very low frequency (LnVLF), low frequency (LnLF) and high frequency (LnHF). Also, normalized low frequency (LF Norm) and high frequency (HF Norm) and LnLF/HF ratio were measured. The study demonstrated that in the normal weight group, women with preeclampsia had significantly higher LnSDNN, LnVLF and LnLF [P > 0.05]. Also, there was no significant difference in the HRV measurements between overweight and obese groups of the women with preeclampsia as well as the controls. The study revealed that preeclampsia could occur in the absence of obesity.
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International Medical Journal

Journal ID : IMJ-10-02-2020-221

Total View : 162

Title : Influence of TiO2 nanoparticles on surface hardness of auto-polymerized acrylic resins utilized for an orthodontic appliance

Abstract : auto-polymerized acrylic resins are widely substances utilized for the fabrication of orthodontic appliances. Such substances have poor mechanical properties and prone to fracture. The purpose of the current study was to evaluate the effect of incorporating titanium dioxide nanoparticles to auto- polymerized acrylic resins in terms of the surface hardness. thirty specimens were constructed in total. They were fabricated from auto-polymerized acrylic resins. Ten specimens were considered as control and the other 20 specimens were reinforced with the titanium dioxide powder at 1% and 2% respectively. All specimens were subjected to the hardness tester. The SPSS version 20 was used to analyze the data, and the Tukey test was used for the comparison among the 3 groups. The results indicated that the titanium dioxide improved the surface hardness strength of acrylic resins. No significant differences were found between control and TiO2 1 groups; TiO21 and TiO2 2 groups where (P>0.05). on the other hand, there was significant difference between control and TiO2 2 groups where P≤0.001.the adding of titanium dioxide increases the surface hardness of auto-polymerized acrylic resins.
Full article

International Medical Journal

Journal ID : IMJ-09-02-2020-219

Total View : 152

Title : Urinary Platelet Factor4 and Vascular Cell Adhesion Molecule-1 as Early Biomarkers of Renal Disease in Systemic Lupus Erythematosus

Abstract : Lupus nephritis (LN) is diagnosed by presence of proteinuria (0.5g per day or a dipstick score of > 3+) or red cell casts on microscopic urine analysis. Assessing histological severity and chronic lesions in LN is by renal biopsy. However, it is invasive and repeated biopsies are needed in monitoring treatment of LN. Therefore, new biomarkers for early diagnosis of lupus renal disease have to be searched. To evaluate urinary platelet factor4 (PF4) and vascular cell adhesion molecule-1(VCAM-1) as early markers of lupus nephritis. 120 patients with systemic lupus erythematosus (SLE) were involved and classified into 3 main groups; group I included 40 patients with inactive SLE, group II included 40 patients with active SLE without lupus nephritis and group III included 40 patients with active SLE with lupus nephritis. All patients were submitted to; urine analysis, complete blood count, fasting blood glucose, serum creatinine, liver function tests, serum complement 3, antinuclear antibody, anti-double stranded DNA level and urinary PF4 and VCAM-1 levels assays. Urinary PF4 and VCAM-1 levels were significantly higher in lupus nephritis group than in the other two groups. The cutoff value of PF4 in prediction of active lupus with nephritis is ≥7.93pg/ng with sensitivity 100% and specificity 90.5% and that of VCAM-1 is ≥783pg/ng with sensitivity 100% and specificity 93.8%. Urinary platelet factor 4 and vascular cell adhesion molecule-1 can serve as early markers for identifying LN.
Full article

International Medical Journal

Journal ID : IMJ-09-02-2020-218

Total View : 132

Title : Correlation Between T peak to end Interval and Left Ventricular Time to Peak Longitudinal Strain in Ischemic Cardiomyopathy Patient

Abstract : Ischemic cardiomyopathy is the most frequent etiology of heart failure with reduced ejection fraction (HFrEF) and a result of ventricular structural, functional, and electrical remodelling. T peak to end (Tpe) interval is an electrocardiographic parameter that represent repolarization heterogeneity and had prognostic value for ventricular arrhythmia. Patients with Ischemic cardiomyopathy face a significant burden of arrhythmias. Mechanical dispersion is a functional remodelling parameter that can be measured by time to peak longitudinal strain using speckle tracking echocardiography. This study aims to assess the relationship between Tpe interval with time to peak longitudinal strain in ischemic cardiomyopathy patients. This study was conducted with observational analytical cross-sectional design. Ischemic cardiomyopathy subjects were included at Dr. Hasan Sadikin General Hospital, Bandung, from August to October 2019. Tpe interval was measured manually with tangential method. Time to peak longitudinal strain was measured using speckle tracking echocardiography. The correlation between Tpe interval and time to peak longitudinal strain was analyzed using Pearson correlation. A total of 30 subjects were included in this study. The average age was 58 ± 8 years old and the average left ventricular ejection fraction was 27 ± 5.5%. The average of Tpe interval was 83.4 + 7.62 ms and the average of time to peak longitudinal strain was 93.13 ± 34.51 ms. The Pearson correlation test showed a significant weak positive correlation (r=-0.386, 95% CI (0.029 – 0.743, p 0.018) between Tpe interval and time to peak longitudinal strain in ischemic cardiomyopathy patients. There was a significant weak positive correlation between Tpe interval and time to peak longitudinal strain in ischemic cardiomyopathy patients.
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International Medical Journal

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Submission Deadline ( Vol 28 , Issue 02 )
10 Feb 2021

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Publish On ( Vol 28 , Issue 01 )
31 Jan 2021