Abstract : This study is conducted to compare the Space occupying lesions of liver its demographic, clinical, imaging & cytopathological correlations & further treatment measures in our institute. Prospective observational study was conducted in our institute from 2019 to October 2021 following approval from ethical committee of hospital. Both Male & Female with all age group patients were included in the study. Mean age of 50 study was 47.36% with highest 53 years & lowest 36years. There were 38(76%) male & 12 (24%)female. 46%were Hepatic abscess, most common lesion of liver followed by metastatic lesions of liver 24%. SOL was most common in 4th & 5th decade. USG was sensitive in all the SOLs but CT was more specific. As per our study, we inferred that abscess was most common space occupying lesion of liver for which ultrasonography was not only diagnostic but also therapeutic, as well in simple hepatic cyst & hydatid cyst. CECT was able to differentiate between Simple hepatic cyst & Multiple liver abscess from Multiple metastatic liver lesions. Hepatic Abscess, Simple Hepatic cyst were 47% managed conservatively. While Hydatid cyst Pigtail was treatment modality..
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Abstract : To determine the frequency of thyroid function abnormalities in patients with septicemia. Faisal Hospital Karachi from July to December 2021. This crossectional study was conducted in the medical wards and Intensive care unit of Faisal Hospital Karachi. Total 100 consecutive patients of either gender age 14 years and above admitted with the diagnosis of septicemia were included and venous blood sample was collected for determination of Free T4 (FT4), Free T3 (FT3), and Thyroid stimulating Hormone (TSH) levels within 24 hours of admission. Those who have known thyroid illness, having history of thyroidectomy, pregnancy, and puerperium and on medications causing alteration of thyroid function were excluded. Statistical Package for Social Sciences (SPSS) version 25 was used for the data analysis. Mean age of the participants was 48.9+ 20.3 years and 48% were male and 52% were females. Around 86% had FT3 lower than 1.4pg/ml, 56% had FT4 lower than 0.8ng/dl and 64% had normal TSH. Around 50% of the participants were expired in this study. In expired patients 44(51.2%) had low freeT3, 36(64.3%) had low T4 and 8 (25%) had low TSH. This study demonstrate that TSH levels are within normal range in most patients while FT3 and FT4 are markedly low, and among those who died more than 50% had low T3 and T4. Thyroid dysfunctions are common among female septic patients as compared to males. There is an association in between abnormal thyroid functions and the mortality in septic patients so these patients should have to be treated appropriately..
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Abstract : Acute abdomen is a common presentation in the emergency department. Acute appendicitis is one of the commonest causes of acute abdomen. Historically, appendicitis has been diagnosed only based on clinical symptoms and signs, and with further advancements aided by laboratory variables such as leukocytes, neutrophils, and CRP. The classical presentation of pain in periumblical region shifting to right iliac fossa with tenderness at McBurney’s point is present in only 50% of cases. The signs and symptoms differ to a great extent according to the position of appendix. The present study was done at our tertiary care center as an attempt to easing the diagnosis of acute appendicitis and to compare clinical examination findings and intra-operative findings. This Descriptive Cross Sectional Study was carried out at a tertiary care hospital and research centre in a Sub-Urban area of Pune to Study The Correlation Of Clinical Signs And Symptoms Of Acute Appendicitis With USG Findings And Intra-Operative Position Of Appendix. The proposal for the study was submitted to the institutional ethics committee and study was undertaken after approval between July 2019 to September 2021. In our study the correlation between the position of appendix between clinical examination and intra-operative findings were found to be statistically significant. Thus the accurate localization of position of appendix requires an amalgamation of all modalities namely clinical examination, ultrasonography and intra-operative findings and not just one isolated modality , thereby reducing the complications associated with a missed diagnosis as well as avoiding unnecessary surgery in false positive cases ultimately reducing morbidity associated with this very much treatable condition..
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Abstract : Acute appendicitis is one of the commonest causes of acute abdomen. The signs and symptoms differ to a great extent and even though the diagnosis is essentially clinical, ultrasound is essential in diagnosing abnormal positions and for pregnant women presenting with acute appendicitis. This present observational cross-sectional study was conducted at Dr. D. Y. Patil Medical college, hospital & Research Centre as an attempt to easing the diagnosis of acute appendicitis. Majority of the patients (36.36%) belonged to the age group of 18-25 years. There were 46.36% male patients while female patients constituted 53.64% of the study group. The most common site of pain was right iliac fossa (61.82%). In our study, the most common position of appendix Intra-Operatively was retrocecal (78.18%) of cases. In our study, on comparison between the ultrasound position and intraoperative position of appendix, the USG had a sensitivity of 100% in paracecal, preileal and subhepatic positions of appendix, 88.9% sensitivity in postileal position, 74% sensitivity in retrocecal position of appendix and 66.7% sensitivity in pelvic position of appendix. On comparison of ultrasound findings and pre-operative clinical findings and intra-operative findings, ultrasound diagnosed appendicitis whether complicated or uncomplicated in 86 cases (78.18 %) whereas gave a normal report in 24 cases (21.81%). We conclude that the accurate localization of position of appendix requires an amalgamation of all modalities namely clinical examination, ultrasonography and intra-operative findings and not just one isolated modality, thereby reducing the complications associated with a missed diagnosis as well as avoiding unnecessary surgery in false positive cases ultimately reducing morbidity associated with this very much treatable condition..
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Abstract : In the present study was to investigate that the prevalence of hypertension in 5-15yrs age of school going children in and around Kancheepuram. Hypertension is one of most important and common cause of morbidity and mortality in the world. It plays an important role development of ischemic heart disease, cerebrovascular disease, cardiac and renal failure. This study was Cross Sectional, Descriptive and analytical study conducted by department of community medicine in rural and urban school going children in an around Kanchipuram from October 2017 to October 2018. The prevalence of hypertension was studied in three groups namely Normal, Pre hypertension and hypertension Out of 1020 school going children’s. 40 had Hypertension, 69 belonged to Prehypertension and 911 belonged to Normal. In the present study we conclude that the risk of hypertension in obese children six times more compared with overweight students..
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